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Vitamin A acid / Tretinoin / Retinoic Acid 302-79-4

Vitamin A acid / Tretinoin / Retinoic Acid 302-79-4

99% up, Cosmetic Grade
  • Product Details

Product Information


Product name

Vitamin A acid / Tretinoin / Retinoic Acid

CAS No.

302-79-4

Molecular Formula

C20H28O2

Molecular Weight

4300.44

Quality Standard

99% up, Cosmetic Grade

Appearance

Light yellow powder


COA of Vitamin A acid / Tretinoin / Retinoic Acid


Items

Specification

Results

Appearance

Yellow Powder

Complies

Odor

Characteristic

Complies

Sieve analysis

100% pass 80mesh

Complies

Heavy Metal

< 10ppm

Complies

Ash

≤1.0%

0.22%

Pb

≤2.0ppm

Not Detected

As

≤0.1pm

Not Detected

Cd

≤0.3ppm

Not Detected

Residual Solvents

≤100ppm

Complies

Residual Pesticide

 Negative

Complies

Total Plate Count

≤1,000cfu/g

Complies

Mold and Yeast

≤100cfu/g

Complies

E.Coli

Negative

Negative

Salmonella

Negative

Negative

Related substance      (HPLC)

98% min

99.8%

Assay

98%

98.22%

Conclusion

 Complies with In-house standard

                                             


Usage


Retinoic acid (is also called Vitamin A acid / Tretinoin /) is a metabolite of vitamin A and plays an important role in cell growth, differentiation and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptor α/β/γ The IC50 is 14 nm. Retinoic acid and PPAR β/δ  The combined Kd value is 17 nm. Retinoic acid can inhibit transcription factor Nrf2 by activating retinoic acid receptor.


Function of Retinoic Acid
1. Retinoic acid is the acid form of vitamin a and so also known as all-trans retinoic acid or atra.

2. Retinoic acid is a drug commonly used to treat acne vulgaris and keratosis pilaris.

3. Retinoic acid is available as a cream or gel.retinoic acid is also used to treat acute promyelocytic leukemia.

4. Retinoic acid can stimulate skin growth and keep epidermic normal.

5. Retinoic acid can slow down skin aging process for solarization, remove tiny wrinkles, and retinoic acid canreduce skin roughness, so skin will become ruddy.

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