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Oxytocin Acetate 50-56-6 Oxytocin Acetate 50-56-6

Oxytocin Acetate 50-56-6
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Basic information of  Oxytocin Acetate :

Name

Oxytocin Acetate

Alias

α-Hypophamine Oxytocic hormone ;Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2

CAS NO.

50-56-6

Molecular Formula

C43H66N12O12S2

Molecular Weight

1007.19

Brief Introduction

Oxytocin Acetate is a peptide hormone


Use of  Oxytocin Acetate:

Oxytocin Acetate is a peptide hormone. Secreted by the posterior pituitary. Synthesized by the hypothalamic paraventricular nucleus and supraoptic nucleus. It consists of 9 amino acids. It is delivered to the neurohypophysis at a rate of 2 mm to 3 mm per day. The methionine residues at positions "1" and "6" form a 6-mer cyclic structure as a disulfide bond. Its physiological role: to stimulate the breast milk secretion, promote the smooth contraction of the uterus during childbirth, and promote the role of maternal love. In addition, it can reduce the level of stress hormones such as adrenal ketone in the human body to lower blood pressure.


COA of Oxytocin Acetate :

TEST

SPECIFICATION

RESULTS

1. Characteristic

White or almost white powder.

White powder

2. Identification


A. HPLC

Retention time conforms to that of  the reference standard

Conforms

B. Amino acids

Asp: 0.90-1.10;Glu: 0.90-1.10

Conforms

Pro: 0.90-1.10;Gly: 0.90-1.10

Leu: 0.90-1.10;Tyr: 0.7-1.05

Half-Cys: 1.4-2.1;Ile: 0.90-1.10

3. pH

3.0-6.0

5

4. Related substances (HPLC)

Impurity A≤1.5%

0.15%

Impurity B≤1.5%

0.20%

Impurity C≤1.5%

Not Detected

Other single impurity≤0.5%

0.13%

Total impurities≤5.0%

0.70%

5. Acetic acid (HPLC)

6.0%-10.0%

7.10%

6. Water(KF)

NMT 5.0%

1.40%

7. Bacterial endotoxins

Less than 300 IU/mg

Conforms

8. AcN(GC)

Not more than 0.041%

Conforms

9. MeOH(GC)

Not more than 0.3%

Conforms

10. Triethylamine(GC)

Not more than 0.032%

Conforms

11. Assay Calculated with reference to anhydrous, acetic acid free substance

93.0%-102.0%

98.80%

on powder

NLT 80.0 %

90.40%



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MORE_DETAIL Oxytocin Acetate 50-56-6

Basic information of  Oxytocin Acetate :

Name

Oxytocin Acetate

Alias

α-Hypophamine Oxytocic hormone ;Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2

CAS NO.

50-56-6

Molecular Formula

C43H66N12O12S2

Molecular Weight

1007.19

Brief Introduction

Oxytocin Acetate is a peptide hormone


Use of  Oxytocin Acetate:

Oxytocin Acetate is a peptide hormone. Secreted by the posterior pituitary. Synthesized by the hypothalamic paraventricular nucleus and supraoptic nucleus. It consists of 9 amino acids. It is delivered to the neurohypophysis at a rate of 2 mm to 3 mm per day. The methionine residues at positions "1" and "6" form a 6-mer cyclic structure as a disulfide bond. Its physiological role: to stimulate the breast milk secretion, promote the smooth contraction of the uterus during childbirth, and promote the role of maternal love. In addition, it can reduce the level of stress hormones such as adrenal ketone in the human body to lower blood pressure.


COA of Oxytocin Acetate :

TEST

SPECIFICATION

RESULTS

1. Characteristic

White or almost white powder.

White powder

2. Identification


A. HPLC

Retention time conforms to that of  the reference standard

Conforms

B. Amino acids

Asp: 0.90-1.10;Glu: 0.90-1.10

Conforms

Pro: 0.90-1.10;Gly: 0.90-1.10

Leu: 0.90-1.10;Tyr: 0.7-1.05

Half-Cys: 1.4-2.1;Ile: 0.90-1.10

3. pH

3.0-6.0

5

4. Related substances (HPLC)

Impurity A≤1.5%

0.15%

Impurity B≤1.5%

0.20%

Impurity C≤1.5%

Not Detected

Other single impurity≤0.5%

0.13%

Total impurities≤5.0%

0.70%

5. Acetic acid (HPLC)

6.0%-10.0%

7.10%

6. Water(KF)

NMT 5.0%

1.40%

7. Bacterial endotoxins

Less than 300 IU/mg

Conforms

8. AcN(GC)

Not more than 0.041%

Conforms

9. MeOH(GC)

Not more than 0.3%

Conforms

10. Triethylamine(GC)

Not more than 0.032%

Conforms

11. Assay Calculated with reference to anhydrous, acetic acid free substance

93.0%-102.0%

98.80%

on powder

NLT 80.0 %

90.40%


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