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Dexamethasone 50-05-2 Dexamethasone 50-05-2

Dexamethasone 50-05-2
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Basic information of Dexamethasone 50-05-2

  • Product Name: Dexamethasone
  • Molecular Formula: C22H29FO5
  • Molecular Weight: 392.46
  • CAS No.: 50-02-2
  • Appearance: White crystalline powder
  • Specifications: USP38/BP2010/EP6

Usage of Dexamethasone 50-05-2

  • It used for autoimmune disease and allergic disease.
  • Such as rheumatoid arthritis; erythematosus; severe bronchial asthma.Nephritic syndrome etc.

COA of Dexamethasone-1

Items

Specifications

Results

Character

White to almost white crystalline powder

Almost white crystalline powder

Specific rotation

+72°to +80°

+76.7°

Identification


Complies by IR

Conforms


Complies by UV≤3.0%

0.7%

Test

Chromatographic Purty

Principal impurity not more than 1.0%

0.07%


Total impurities not more than 2.0%

0.36%

Loss on drying

Not more than 0.5%

0.1%

Residue Solvent

Not more than 0.2%

0.07%

Chloroform

Not more than 60ppm

Undetected

Methanol

Not more than 1000ppm

210ppm

Ethyl Acetate

Not more than 300ppm

14ppm

Assay

Contains 97.0% to 102.0% of C22H29FO5 Calculated on dried basis

99.5%

Conclusion

The goods conforms to USP38

COA of Dexamethasone -2

Items

Specifications

Results

Character

White or almost white cystalline powder

Almost white crystalline Powder

Specific Rotation

+75°~+80°

+76.9°

Identification

Complies by IR

Conforms


Complies by TLC

Conforms

Test



Chromatographic Purity

Principal impurity not more than 0.5

0.05%


Total impurities not more than 1.0%

0.24%

Loss on drying

Not more than 0.5%

0.1%

Assay

97%~103% (C22H29FO5 Calculated on dried basis)

99.1%

Conclusion

The results can conforms to EP5/BP2007/EP6/BP2010



MORE_DETAIL Dexamethasone 50-05-2

Basic information of Dexamethasone 50-05-2

  • Product Name: Dexamethasone
  • Molecular Formula: C22H29FO5
  • Molecular Weight: 392.46
  • CAS No.: 50-02-2
  • Appearance: White crystalline powder
  • Specifications: USP38/BP2010/EP6

Usage of Dexamethasone 50-05-2

  • It used for autoimmune disease and allergic disease.
  • Such as rheumatoid arthritis; erythematosus; severe bronchial asthma.Nephritic syndrome etc.

COA of Dexamethasone-1

Items

Specifications

Results

Character

White to almost white crystalline powder

Almost white crystalline powder

Specific rotation

+72°to +80°

+76.7°

Identification


Complies by IR

Conforms


Complies by UV≤3.0%

0.7%

Test

Chromatographic Purty

Principal impurity not more than 1.0%

0.07%


Total impurities not more than 2.0%

0.36%

Loss on drying

Not more than 0.5%

0.1%

Residue Solvent

Not more than 0.2%

0.07%

Chloroform

Not more than 60ppm

Undetected

Methanol

Not more than 1000ppm

210ppm

Ethyl Acetate

Not more than 300ppm

14ppm

Assay

Contains 97.0% to 102.0% of C22H29FO5 Calculated on dried basis

99.5%

Conclusion

The goods conforms to USP38

COA of Dexamethasone -2

Items

Specifications

Results

Character

White or almost white cystalline powder

Almost white crystalline Powder

Specific Rotation

+75°~+80°

+76.9°

Identification

Complies by IR

Conforms


Complies by TLC

Conforms

Test



Chromatographic Purity

Principal impurity not more than 0.5

0.05%


Total impurities not more than 1.0%

0.24%

Loss on drying

Not more than 0.5%

0.1%

Assay

97%~103% (C22H29FO5 Calculated on dried basis)

99.1%

Conclusion

The results can conforms to EP5/BP2007/EP6/BP2010


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