NMN (β-NicoTinamide Monocucleotide; beta-NicoTinamide Monocucleotide) is a very popular anti-aging substance in recent years. However, many people worry that it is not safe to take NMN for a long time. An anti-aging platform in China summarized this:
1. NMN is an endogenous substance in the human body, which is ubiquitous and always present in the body; and it is the coenzyme NAD+ that directly plays a role after supplementing with NMN, and the coenzyme NAD+ plays a role in catalyzing the reaction in the human body, not directly Reactant.
2. NMN also exists in many natural foods. We can easily consume NMN simply by taking supplements instead of taking health products. These foods are:
3. The most direct evidence to verify the safety of NMN is experiment. In an animal experiment conducted by Professor David Sinclair of Harvard University, mice took NMN for one year, and their age-related physiological function decline and metabolic loss were significantly improved without any obvious side effects. In human clinical trials, although the four currently registered cases have not disclosed detailed experimental data, two trials have passed Phase I clinical trials, and Phase II clinical trials have started early. Phase I is usually a safety study. NMN can pass Phase I clinical and enter Phase II, and its safety and tolerability to humans have been preliminarily verified. Another experiment confirmed that after long-term use of NMN in healthy people, the expression of sirtuins protein increased, and the expression of multiple hormones increased, and the experimental results were positive. Sirtuins protein is a class of highly conserved deacetylases from bacteria to humans. It participates in important physiological functions such as DNA repair, genome stabilization, neuroprotection, insulin secretion, vascular protection, and regulates a variety of life-related signal pathways to achieve anti-aging Effect.
4. Studies have found that the natural NMN in organisms is β-NMN, and other isomers such as α-NMN have no activity. However, if the conventional synthetic method is used to synthesize NMN, the content of β-NMN is only 60%, so the synthesized NMN has extremely high safety risks. The NMN provided by SINOWAY undergoes extremely difficult chiral separation. After a third-party center testing and testing, all the NMNs we provide are β-NMN with natural structure.
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