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What is the relationship and difference of NMN and NAD+?

What is the relationship and difference of NMN and NAD+?

Dec 27, 2021
The NMN (β-Nicotinamide Mononucleotide, Beta-Nicotinamide Mononucleotide) is an inherent substance in the human body and one of the precursor substances of NAD+. NMN plays a role, and the core is realized by transforming into NAD+ .

NAD+ is an important coenzyme of the tricarboxylic acid cycle in the human body (the tricarboxylic acid cycle is the final metabolic pathway of the three major nutrients: carbohydrates, lipids, and amino acids, and it is also the hub of the metabolism of carbohydrates, lipids, and amino acids), which promotes sugar , Fat, amino acid metabolism, participate in energy synthesis. NAD+ is the only substrate of Coenzyme I depleting enzyme (DNA) repair enzyme PARP, the only substrate of longevity protein Sirtuins, the only substrate of cyclic ADP ribose synthetase CD38/157), NAD+ is very involved in intracellular reactions. Extensive, as many as thousands of species. At the same time, studies have shown that with age, the synthesis of NAD+ gradually decreases, and the consumption gradually increases, so the total amount of NAD+ becomes less and less. This reduction has a strong correlation with aging and disease.

NAD+ is so important, but NAD+ in the body decreases with age. As a precursor of NAD+, NMN can effectively transform and supplement the NAD+ level in the body through exogenous consumption, which can delay the aging process of the human body.


Tags : NMN NAD+ NMN NAD
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