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Zidovudine 30516-87-1

Zidovudine 30516-87-1

99% up by HPLC, USP, EP
  • Product Details

Product Information


Product name

Zidovudine

CAS No.

30516-87-1

Molecular Formula

C10H13N5O5

Molecular Weight

283.24

Quality Standard

99% up, USP,EP

Appearance

White powder


COA of Zidovudine


  TEST

STANDARD

RESULT

Appearance:

White powder

Complies

Loss on drying

6.0%

3.83%

Heavy metals

< 10ppm

Complies

As

3.0 ppm

Complies

Pb

3.0 ppm

Complies

Cd

0.5 ppm

Complies

Microbiology

Total plate count

< 1000 cfu/g

326 cfu/g

Yeast & Mold

< 100 cfu/g

28 cfu/g

E. Coli

Negative

Complies

S. Aureus

Negative

Complies

Salmonella

Negative

Complies

Assay

995-101%

99,5%

Conclusion

Conforms with USP standard


Usage


Function of Zidovudine

Zidovudine is an antiviral drug used in the treatment of patients with AIDS or AIDS-related syndromes and immunodeficiency virus (HIV) infection. It is highly active against retroviruses including human immunodeficiency virus (HIV) in vitro. In virus-infected cells, it is phosphorylated by cellular thymidine kinase to zidovudine triphosphate, which can selectively inhibit HIV reverse transcriptase, leading to the termination of HIV chain synthesis and preventing HIV replication. On March 19, 1987, the US Food and Drug Administration approved the drug for marketing. Zidovudine is the world's first anti-AIDS drug approved by the US FDA.

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