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Tripterygium Wilfordii Extract / Leigongteng Extract / Triptolide 38748-32-2

Tripterygium Wilfordii Extract / Leigongteng Extract / Triptolide 38748-32-2

98% up
  • Product Details

Product Information


Product name

Tripterygium Wilfordii Extract / Leigongteng Extract / Triptolide

CAS No.

38748-32-2

Molecular Formula

C20H24O6

Molecular Weight

360.40

Quality Standard

98% up

Appearance

White powder


COA of Triptolide


TEST

SPECIFICATION

RESULTS

Appearance

White  powder

Complies

Odor

Characteristic

Complies

 Particle Size

100% pass 80 mesh

Complies 

Loss on Drying

≤5.0%

2.5%

Ash

≤1.0%

0.2%

Heavy Metals

≤10ppm

Complies

Pb

≤1ppm

Complies

As

≤1ppm

Complies

Microbiological:

Total Plate Count

≤1.000 cfu/g

Complies

Yeast & Mold

≤1.00 cfu/g

Complies

E. Coil

Negative

Complies

Salmonella

Negative

Complies

Staphylococcus

Negative

Complies

Assay

≥98.0%

99.11%

Conclusion

Conforms with In-house standards

Identification method:Mass, NMR
Analysis method:HPLC-DAD or/and HPLC-ELSD


Usage


Function of Triptolide

Triptolide is a traditional Chinese medicine with a long and widely used history. Triptolide (TPL) is one of the main active ingredients of Tripterygium wilfordii. Tripterygium wilfordii is a natural product with a variety of biological activities. It is derived from the root of the traditional Chinese medicine Tripterygium wilfordii. Studies have shown that it has anti-oxidant, anti-rheumatoid, anti-senile dementia and anti-cancer effects. It is a diterpene lactone with multiple biological activities. It is derived from the root of the Chinese medicine Tripterygium wilfordii. It is the main active ingredient in the treatment of rheumatoid tripterygium wilfordii tablets and tripterygium wilfordii polyglycoside tablets.

  Modern research shows that triptolide not only has anti-rheumatoid effects, but also anti-cancer effects. A large number of in vivo and in vitro studies have proved that triptolide has good anti-tumor activity against a variety of cancers such as leukemia, breast cancer, pancreatic cancer and lung cancer. Recent studies have found that in addition to specifically affecting certain proteins and signal pathways, triptolide can also inhibit a wide range of gene transcription, but its mechanism of action needs to be further clarified.

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