Trilostane 13647-35-3

98% up by HPLC

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Product Details

Product Information

Product name	Trilostane
CAS No.	13647-35-3
Molecular Formula	C20H27NO3
Molecular Weight	329.43
Quality Standard	98.0% up by HPLC
Appearance	White or almost white powder

COA

ANALYSIS	SPECIFICATION	RESULTS
Appearance	White or almost white powder	Almost white powder
Identification IR	The infrared absorption spectrum of the sample is concordant with the reference spectrum	Conforms
Specific optical rotation	+137 to +139	+139
Loss on drying	≤0.5%	0.41%
Heavy metals	≤20ppm	<20ppm
Residue on ignition	≤0.1%	0.06%
Related substances	Any impurity ≤ 0.5%	0.05%
Related substances	Total impurities ≤ 1.0%	0.19%
Residual solvents	Ethanol ≤ 5000ppm	175 ppm
	Dichloromethane ≤ 600ppm	Not detected
	Ethyl acetate ≤ 5000ppm	Not detected
	Ethyl formate ≤ 5000ppm	Not detected
	Dimethyl sulfoxide ≤ 5000ppm	4245ppm
Purity	≥99.0%	99.8%
Assay((on dried bases)	980% - 102.0%	98.8%
Conclusion	The product meets the in-house standard

Usage

What is Trilostane?

Trilostane is primarily used in veterinary medicine to treat Cushing's syndrome (hyperadrenocorticism) in dogs.Trilostane works by inhibiting an enzyme called 3-beta-hydroxysteroid dehydrogenase, which is involved in the production of cortisol. By blocking this enzyme, Trilostane helps reduce the production of cortisol, alleviating the symptoms associated with Cushing's syndrome in dogs.