Sinoway Industrial Co., Ltd.

Miglitol 72432-03-2 Miglitol 72432-03-2

Miglitol 72432-03-2
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Basic information of Miglitol

Name

Miglitol  

Alias

GLYSET; Seibule; MIGLITOL; Plumarol; BAY 1099; Diastabol; 
BAY-m-1099; Miglitol(TCI); Miglitol (Glyset); N-(2-Hydroxyethyl)moranoline

CAS NO.

72432-03-2

Molecular Formula

C8H17NO5

Molecular Weight

207.22

Quality Standard

JP/ 98%min

Grade Standard

Medicine grade

Package Size

1kg/bag; 5kg/ bag; 25kg/drum

Use of Miglitol

Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body.

Miglitol inhibits glycoside hydrolase enzymes called alpha-glucosidases. Since miglitol works by preventing digestion of carbohydrates, it lowers the degree of postprandial hyperglycemia. It must be taken at the start of main meals to have maximal effect. Its effect will depend on the amount of non-monosaccharide carbohydrates in a person's diet.

COA of Miglitol

ITEMS

STANDARDS

RESULTS

DESCRIPTION

OFF-WHITE TO WHITE CRYSTALLINE POWDER

WHITE CRYSTALLINE POWDER

IDENTIFICATION

IR SPECTRUM OF SAMPLE COMPLIES WITH THAT OF STANDARD

CONFORMS

MELTING POINT

142.0~146.0℃

143.5~145.5℃

SEPCIFIC OP[TICAL ROTATION

-4.0°~ -8.0°

-7.6°

PH

7.0-8.0

7.5

WATER

NMT1.0%

0.20%

RESIDUE ON IGNITION

NMT0.1%

0.06%

HEAVY METALS

NMT 20PPM

<20PPM

RESIDUAL SOLVENTS

METHANOL         NMT3000PPM

ETHANOL          NMT5000PPM

ISO-PROPANOL    NMT5000PPM

1139.16PPM

1558.45PPM

NOT DETECTED

RELATED SUBSTANCE

(HPLC)

SINGLE IMPURITY    NMT 0.1%

0.05%

TOTAL IMPURITIES   NMT 1.0%

0.10%

ASSAY

99.0-102.0%

99.32%

CONCLUSION: CONFORM WITH THE ENTERPRISE STANDARD


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MORE_DETAIL Miglitol 72432-03-2

Basic information of Miglitol

Name

Miglitol  

Alias

GLYSET; Seibule; MIGLITOL; Plumarol; BAY 1099; Diastabol; 
BAY-m-1099; Miglitol(TCI); Miglitol (Glyset); N-(2-Hydroxyethyl)moranoline

CAS NO.

72432-03-2

Molecular Formula

C8H17NO5

Molecular Weight

207.22

Quality Standard

JP/ 98%min

Grade Standard

Medicine grade

Package Size

1kg/bag; 5kg/ bag; 25kg/drum

Use of Miglitol

Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body.

Miglitol inhibits glycoside hydrolase enzymes called alpha-glucosidases. Since miglitol works by preventing digestion of carbohydrates, it lowers the degree of postprandial hyperglycemia. It must be taken at the start of main meals to have maximal effect. Its effect will depend on the amount of non-monosaccharide carbohydrates in a person's diet.

COA of Miglitol

ITEMS

STANDARDS

RESULTS

DESCRIPTION

OFF-WHITE TO WHITE CRYSTALLINE POWDER

WHITE CRYSTALLINE POWDER

IDENTIFICATION

IR SPECTRUM OF SAMPLE COMPLIES WITH THAT OF STANDARD

CONFORMS

MELTING POINT

142.0~146.0℃

143.5~145.5℃

SEPCIFIC OP[TICAL ROTATION

-4.0°~ -8.0°

-7.6°

PH

7.0-8.0

7.5

WATER

NMT1.0%

0.20%

RESIDUE ON IGNITION

NMT0.1%

0.06%

HEAVY METALS

NMT 20PPM

<20PPM

RESIDUAL SOLVENTS

METHANOL         NMT3000PPM

ETHANOL          NMT5000PPM

ISO-PROPANOL    NMT5000PPM

1139.16PPM

1558.45PPM

NOT DETECTED

RELATED SUBSTANCE

(HPLC)

SINGLE IMPURITY    NMT 0.1%

0.05%

TOTAL IMPURITIES   NMT 1.0%

0.10%

ASSAY

99.0-102.0%

99.32%

CONCLUSION: CONFORM WITH THE ENTERPRISE STANDARD

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