Eptifibatide 188627-80-7

MORE_DETAIL Eptifibatide 188627-80-7

Basic information of Eptifibatide:

Name	Eptifibatide
CAS NO.	188627-80-7
Molecular Formula	C35H49N11O9S2
Molecular Weight	831.96
Grade Standard	Medicine grade  / 99% min / FDA / DMF
Package Size	1kg/bag; 5kg/tin; 25kg/drum
Storage:	Keep in a well-closed container, protected from light and stored at a temperature of 2 to 8

Use of Eptifibatide:

Eptifibatide is an antiplatelet agent of glycoprotein IIb / IIIa inhibitors. Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the Southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of arginine-glycine-aspartate-mimetic and reversibly binds to platelets. The half-life of eptifibatide is short. This drug is the third inhibitor of GPIIb / IIIa, which has been widely found after the specific antibodies abciximab and non-peptide tirofiban entered the global market.

Indications
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
The drug should exclusively be used in hospitalized patients both because of the serious degree of patients' illness and because of the possible side-effects of eptifibatide.

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