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Lenalidomide 191732-72-6

Lenalidomide 191732-72-6

98% up, USP/BP
  • Product Details

Product Information


Product name

Lenalidomide

CAS No.

191732-72-6

Molecular Formula

C13H13N3O3

Molecular Weight

259.26062

Quality Standard

98% up, Medicine Grade

Appearance

White to light yellow crystalline powder


COA of Lenalidomide


Test Items

Specifications

Results

Appearance

White to light yellow crystalline powder

conforms

Water content

≤ 4.0%

0.021

Residuce on ignition

≤ 0.5%

0.0032

Residual Solvents

Methanol≤ 3000ppm

1400ppm

 

Acetonitrile≤ 410ppm

not detected

 

Carbon tetrachloride≤ 4ppm

not detected

 

Tetrahydrofuran≤ 720ppm

250ppm

 

Dimethylformamide

320ppm

 

≤ 550ppm

 

Related Substance

Single Impurity≤1%

0.004

 

Total Impurity≤1.5%

0.008

Assay

≥98.0%

0.996

Test Items

Specifications

Results

Appearance

White to light yellow crystalline powder

conforms

Water content

≤ 4.0%

0.021

Residuce on ignition

≤ 0.5%

0.0032

Residual Solvents

Methanol≤ 3000ppm

1400ppm

 

Acetonitrile≤ 410ppm

not detected

 

Carbon tetrachloride≤ 4ppm

not detected

 

Tetrahydrofuran≤ 720ppm

250ppm

 

Dimethylformamide

320ppm

 

≤ 550ppm

 

Related Substance

Single Impurity≤1%

0.004

 

Total Impurity≤1.5%

0.008

Assay

≥98.0%

99.6%


Usage


Function of Lenalidomide

1. Lenalidomide API is an anti-tumor drug developed by Celgene biopharmaceutical company. The chemical structure is similar to thalidomide, which has multiple functions such as anti-tumor, immune regulation and anti-angiogenesis.

2. Lenalidomide inhibits the secretion of proinflammatory cytokines and increases the secretion of anti-inflammatory cytokines in peripheral blood monocytes.

3. Lenalidomide can also inhibit the expression of cyclooxygenase 2(cox-2), but it has no effect on cox-1.

4. Lenalidomide besides can be used to treat MDS and MM, for multiple myeloma, leukemia, metastatic renal cell carcinoma, solid tumor, idiopathic generalized the degeneration amylum and with marrow unripe systemic bone marrow fibrosis disease have certain curative effect.

5. Lenalidomide is currently the most effective drug to treat multiple myeloma.

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If you are interested in our products and want to know more details,please leave a message here,we will reply you as soon as we can.

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