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Dapagliflozin 461432-26-8

Dapagliflozin 461432-26-8

99% up by HPLC, GMP application / PMDA / DMF
  • Product Details

Product Information


Product name

Dapagliflozin

CAS No.

461432-26-8

Molecular Formula

C21H25ClO6

Molecular Weight

408.879

Quality Standard

98% up by HPLC

Appearance

White to pale yellow powder


COA of Dapagliflozin


ITEMS

SPECIFICATION

RESULT

Appearance

White to pale yellow powder

Conforms

Related substance

Purity(HPLC) 99.0%

99.8%

Single impurity 0.5%

0.08% max

Total impurity 1.0%

0.2%

Water

3.0%

1.5%

Conclusion

The sample meets the standard requirements


Usage


Dapagliflozin is a new type of antidiabetic drug, a sodium-glucose cotransporter 2 inhibitor, and the first SGLT2 inhibitor approved for the treatment of type 2 diabetes. Important choice for improving glycemic control as an adjunct to diet and exercise in adults with type 2 diabetes.


*Products under the patent are only for R&D use


Key Intermediates of Dapagliflozin:

(1) 5-Bromo-2-chlorobenzoic acid 

CAS No.: 21739-92-4

(2) D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-

CAS No.: 461432-25-7

(3) 5-bromo-2-chloro-4'-ethoxydiphenylmethane

CAS No.: 461432-23-5

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