Dapagliflozin 461432-26-8

99% up by HPLC, GMP application / PMDA / DMF

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Product Information

Product name	Dapagliflozin
CAS No.	461432-26-8
Molecular Formula	C21H25ClO6
Molecular Weight	408.879
Quality Standard	98% up by HPLC
Appearance	White to pale yellow powder

COA of Dapagliflozin

ITEMS	SPECIFICATION	RESULT
Appearance	White to pale yellow powder	Conforms
Related substance	Purity(HPLC) ≥ 99.0%	99.8%
	Single impurity ≤ 0.5%	0.08% max
	Total impurity ≤ 1.0%	0.2%
Water	≤ 3.0%	1.5%
Conclusion	The sample meets the standard requirements

Usage

Dapagliflozin is a new type of antidiabetic drug, a sodium-glucose cotransporter 2 inhibitor, and the first SGLT2 inhibitor approved for the treatment of type 2 diabetes. Important choice for improving glycemic control as an adjunct to diet and exercise in adults with type 2 diabetes.

*Products under the patent are only for R&D use

Key Intermediates of Dapagliflozin:

(1) 5-Bromo-2-chlorobenzoic acid

CAS No.: 21739-92-4

(2) D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-

CAS No.: 461432-25-7

(3) 5-bromo-2-chloro-4'-ethoxydiphenylmethane

CAS No.: 461432-23-5

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