Bromhexine hydrochloride 611-75-6

98.5% up by HPLC, GMP, DMF, BP2015

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Product Details

Product Information

Product name	Bromhexine hydrochloride; Bromhexine HCL
CAS No.	611-75-6
Molecular Formula	C14H20Br2N2.HCl
Molecular Weight	412.595
Molecular Structure
Quality Standard	98.5% up by HPLC
Appearance	White or almost white crystalline powder

COA

ANALYSIS	SPECIFICATION	RESULTS
Appearance	White or almost white crystalline powder	Conforms
Solubility	Very slightly soluble in water,slightly soluble in alcohol and in methylene chloride.	Conforms
Identification First identification: A E Second identification: B C D E	A: IR	Conforms
	B: TLC	Conforms
	C: Brownish-yellow color develops in the lower layer.	Conforms
	D: Reaction of primary aromatic amines	Conforms
	E: Reaction of chlorides	Conforms
Appearance of solution	The solution is clear and not more intensely colored than reference solution Y6	Conforms
Loss on drying	≤1.0%	0.12%
Heavy metals	≤20ppm	Conforms
Sulphated Ash	≤0.1%	0.06%
Related substance	Impurity A ≤ 0.10%	Conforms
	Impurity B ≤ 0.10%	Conforms
	Impurity C ≤ 0.10%	Conforms
	Impurity D ≤ 0.10%	Conforms
	Impurity E ≤ 0.10%	Conforms
	Single impurity ≤ 0.20%	0.07%
	Total impurities ≤ 0.30%	0.19%
Assay((on dried bases)	98.5% - 101.5%	99.8%
Conclusion	The product meets BP2015

Usage

What is Bromhexine hydrochloride?

Bromhexine hydrochloride (Bromhexine HCl) is a medication commonly used as a mucolytic agent. It helps to alleviate respiratory conditions characterized by excessive mucus or phlegm production. Bromhexine HCl is available in various forms, including tablets, syrups, and cough syrups. The primary mode of action of Bromhexine HCl is the stimulation of the production and secretion of thin and less viscous mucus in the respiratory tract. This action helps to break down and loosen thick mucus, making it easier to expectorate or cough out. By thinning the mucus, Bromhexine HCl can help relieve cough and congestion associated with respiratory conditions such as bronchitis, chronic obstructive pulmonary disease (COPD), and other respiratory tract infections. In addition to its mucolytic properties, Bromhexine HCl also exhibits certain other effects, including anti-inflammatory and antioxidant properties. These additional effects may contribute to its therapeutic benefits in managing respiratory conditions.