Atomoxetine hydrochloride 82248-59-7

99% up by HPLC, GMP

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Product Details

Product Information

Product name	Atomoxetine hydrochloride; Atomoxetine HCL
Alias	Benzenepropanamine,N-methyl-g-(2-methylphenoxy)-,hydrochloride, (R)-;Benzenepropanamine, N-methyl-g-(2-methylphenoxy)-, hydrochloride, (gR)- (9CI);
CAS No.	82248-59-7
Molecular Formula	C17H22ClNO
Molecular Weight	291.821
Molecular Structure
Quality Standard	99% up by HPLC
Appearance	White crystalline powder

COA

ANALYSIS	SPECIFICATION	RESULTS
Appearance	Off-white or white powder	Conforms
Solubility	It is easy to soluble in absolute ethanol, slightly soluble in water, and almost insoluble in heptane.	Conforms
Melting point	166^。C ~ 169^。C	167.5^。C-168^。C
Specific rotation	-34.0^。~ -38^。	Conforms
Identification	Retention time of the main peak of the test product and the main peak of the reference product are the same	Conforms
	The infrared light absorption spectrum should be consistent with the reference spectrum.	Conforms
	Identification of chlorides in aqueous solution of this product	Positive
Related substances	O-cresol≤0.10%	Conforms
	Amphetamine≤0.10%	N.D.
	Phenylpropanolamine≤0.10%	N.D.
	Dimethy tomoxetine≤0.10%	N.D.
	Desmethoxetine≤0.3%	0.03%
	The single impurity≤0.10%	0.04%
	The total impurities≤0.50%	0.14%
Enantiomer	≤0.15%	0.001%
M-tomoxetine	≤0.10%	N.D.
P-tomoxetine	≤0.10%	N.D.
Residual solvents	Methanol≤0.30%	0.18%
	Dichloromethane≤0.06%	N.D.
	N-hexane≤0.029%	N.D.
	Ethyl acetate≤0.50%	N.D.
	Cyclohexane≤0.388%	N.D.
	Toluene≤0.089%	N.D.
Loss on drying	≤0.50%	0.09%
Residue on ignition	≤0.10%	0.04%
Heavy metal	≤10ppm	Conforms
Assay(drying)	98.0% - 102.0%	99.5%
Conclusion	The product meets enterprise standard.

Usage

What is Atomoxetine hydrochloride?

Atomoxetine hydrochloride (Atomoxetine HCL) is a medication that is primarily used to treat attention deficit hyperactivity disorder (ADHD) in children, adolescents, and adults. Atomoxetine hydrochloride belongs to a class of drugs known as selective norepinephrine reuptake inhibitors (SNRIs). Unlike other medications used to treat ADHD, atomoxetine does not belong to the stimulant class. Instead, it works by increasing the levels of norepinephrine, a neurotransmitter involved in regulating attention, in the brain. By affecting the balance of neurotransmitters, atomoxetine helps to improve attention, reduce impulsivity, and decrease hyperactivity in individuals with ADHD. It is believed to have a longer-lasting effect than stimulant medications and does not carry the risk of abuse or dependence.