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 What is Octreotide?

What is Octreotide?

Apr 11, 2022
Octreotide is a synthetic octapeptide derivative of natural somatostatin. Its pharmacological action is similar to that of somatostatin, but the effect lasts longer. Octreotide can inhibit growth hormone and thyrotropin, inhibit the secretion of gastric acid, pancreatic enzymes, glucagon and insulin, reduce gastric motility and gallbladder emptying, inhibit the secretion of cholecystokinin and secretin, reduce the secretion of the pancreas, which has a direct protective effect on the pancreatic parenchyma cell membrane. Reduce splanchnic blood flow, reduce portal pressure, reduce excessive intestinal secretion, increase intestinal absorption of water and sodium, for emergency treatment of esophagus-gastric variceal bleeding caused by acromegaly and liver cirrhosis, In combination with specific treatments (eg, endoscopic sclerotherapy), it can also prevent postoperative complications of pancreatic surgery and relieve symptoms and signs associated with gastroenteroendocrine tumors.
Tags : Octreotide Octreotide acetate 83150-76-9

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