2,4-Dichloropyrimidine / Osimertinib intermediate 3934-20-1

99% up by HPLC

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Product Details

Product Information

Product name	2,4-Dichloropyrimidine； 2,6-Dichloropyrimidine; Pyrimidine, 2,4-dichloro-; Osimertinib intermediate
CAS No.	3934-20-1
Molecular Formula	C4H2Cl2N2
Molecular Weight	148.979
Molecular Structure
Quality Standard	98% up by HPLC
Appearance	Pale yellow or off-white powder

COA

ANALYSIS	SPECIFICATION	RESULTS
Melting point	58-60℃	58.5-60℃
Appearance	Pale yellow or off-white powder	Conforms
Water	≤ 0.2%	0.08%
Residue on ignition	≤ 0.3%	0.23%
Assay (by HPLC)	≥ 98.0%	99.2%
Conclusion	The product meets enterprise standard CDMO service: We can customized manufacturing according to your requirement.

Usage

What is 2,4-Dichloropyrimidine?

2,4-Dichloropyrimidine is one of key intermediates of Osimertinib. Osimertinib is used to treat locally advanced or metastatic non-small-cell lung cancer (NSCLC), if the cancer cells are positive for the T790M mutation in the gene coding for EGFR or for activating EGFR mutations.