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AMIKACIN INTERMEDIATE 40371-50-4 CBZ-L-HABA

AMIKACIN INTERMEDIATE 40371-50-4 CBZ-L-HABA

99% up by HPLC, medical grade
  • Product Details

Product Information


Product name

Amikacin intermediate 262368-30-9

Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy Butyric (CBZ-L-HABA)

Molecular Formula

C12H15NO5

Molecular Weight

253.25

CAS No.

40371-50-4

Quality Standard

99% up by HPLC, medical grade

Appearance

White powder


COA of Amikacin Intermediate 40371-50-4


ITEMS

SPECIFICATION

RESULTS

DESCRIPTION

WHITE OR OFF-WHITE SOLID POWDER

OFF-WHITE SOLID POWDER

MELTING RANGE

75.0℃-79.0℃

76.0℃-78.5℃

LOSS ON DRYING

≤1.0%

0.12%

SPECIFIC ROTATION

-3.5°to -7.0°

-4.75°

ASSAY

≥98%

99.15%

RESIDUE ON IGNITION

≤1.0%

0.05%

CONCLUSION

CONFORMS TO THE ENTERPRISE STANDARD

STORAGE

AIRTIGHT, PROTECTED FROM LIGHT, IN COOL AND DRY PLACE.


Usage


Amikacin intermediate 262368-30-9(Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy Butyric (CBZ-L-HABA)) is a key intermediate of Amikacin. Amikacin is an aminoglycoside antibiotic, a white or off-white powder or a crystalline powder; almost odorless and tasteless. Its mechanism of action is to act on ribosomes in bacteria, inhibit bacterial protein synthesis, and destroy the integrity of bacterial cell walls, causing bacterial cell membrane destruction and cell death. Suitable for infections caused by Gram-negative bacilli and penicillin-resistant Staphylococcus aureus.

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