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Product Information |
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Product name |
Troxerutin |
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CAS No. |
7085-55-4 |
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Molecular Formula |
C33H42O19 |
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Molecular Weight |
742.685 |
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Quality Standard |
95% up |
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Appearance |
Yellowish-green, crystalline powder |
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COA
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ANALYSIS |
SPECIFICATION |
RESULTS |
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Appearance |
Yellowish-green, crystalline powder |
Yellowish-green, crystalline powder |
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Identification |
The infrared absorption pattern should be consistent with reference product |
Conforms |
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The principal peak in the chromatogram obtained with the test solution is similar to the chromatogram obtained with the reference solution (a) |
Conforms |
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Related substance |
Purity of main peak ≥ 80.0% |
89.5% |
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2.7% |
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Other single component peak ≤ 5.0% |
2.1% |
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Ethylene oxide |
≤ 1ppm |
Not detected |
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Methanol |
≤ 3000ppm |
410ppm |
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Loss on drying |
≤5.0% |
0.68% |
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Sulphated ash |
≤0.4% |
0.07% |
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Assay |
95.0% - 105.0% |
100.8% |
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Microbial Limit |
45cfu/g |
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TYMC≤100cfu/g |
<10cfu/g |
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Escherichia coli: Not detected in 1g |
Not detected |
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Conclusion |
The sample complies with the Ph.Eur.11.2. |
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Usage |
Troxerutin, also known as rutin derivative or venoruton, is a bioflavonoid compound derived from natural sources such as the Japanese pagoda tree, sophora japonica, and other plants. It is a yellowish-white crystalline powder that is highly soluble in water.
Pharmacological Effects
1. Anti-inflammatory Properties: Troxerutin has been shown to reduce the production of inflammatory
2. Antioxidant Properties: It acts as a powerful antioxidant by neutralizing free radicals, thus protecting cells and tissues from oxidative stress and damage.
3. Anti-cancer Properties: Troxerutin has demonstrated anti-cancer activity by inhibiting the growth and spread of cancer cells, and protecting healthy cells from damage caused by cancer treatments like chemotherapy and radiation therapy.
4. Vascular Effects: It helps to improve blood flow, reduce the risk of blood clots, and exhibits anti-thrombotic properties. Troxerutin also has a weak vasoconstrictive effect, reducing capillary permeability and fragility, thereby preventing edema caused by increased vascular permeability.