Product Name: Natural Borneol
Other Names: dextran borneol
Appearance: white flake crystalline
Specification: D-Borneol ≥ 96% %
CAS NO.: 464-43-7
Detection Method: HPLC
2. Introduction of Natural Borneol:
Borneol is known as borneol in Chinese medicine, and belongs to "aromatic resuscitation" medicinal materials. Chinese medicine holds that borneol is a "fragrant" product, which has the effect of enlightening the mind and awakening the mind. It is suitable for the syndromes of dizziness and convulsion.
Natural borneol fragrance elegant, fragrant, refreshing, known as plant musk, in the essence, perfume, cosmetics industry, often prepared lavender, cologne, pine needle and other fragrant products. It has the functions of refreshing the brain, repelling mosquitoes and flies, antisepsis and preventing mildew. It is often used to prepare refreshing agents, repelling mosquitoes and high-grade preservatives. In addition, it is also widely used in food preservation and chewing gum, tobacco, daily chemical and other industries. At present, the demand for natural borneol (dextran borneol) is high in foreign high-end perfume and essence.
Natural borneol has been used to inhibit the growth of cancer cells, such as natural borneol developed in Germany has been patented, a number of natural borneol additives for the treatment of nasopharyngeal cancer, breast cancer, rectal cancer, cervical cancer, vaginal cancer, vascular cancer, malignant lymphoma and cancer pain.
According to the U. S. FDA demonstrated that the body found 13 kinds of inflammation, natural borneol can effectively block 12 kinds of natural borneol can be called the guardian saint of healthy life! In addition, natural borneol can also be used in health products, cosmetics, daily necessities, drinking products, can protect the eyes, skin care, beauty, incense, mosquito repellent, disinfection and sterilization.
In clinical practice, borneol is mainly used for febrile diseases, syncope, and stroke phlegm syncope, syncope, nausea, sudden collapse and other symptoms of autism. For sores and scabies, sores, sores, sores, sores, sores, throats and eye diseases, this product has the effect of detumescence and pain relief, and anti-corrosion, anti-itching, mainly for external use, with borax, Xuanming powder, can be used to treat gingival swelling and pain, throat swelling and sores, mouth sores and other symptoms; such as nasal congestion, with a small amount of Bingbosan blowing nose, nasal obstruction; other such as traditional Chinese medicine surgery, surgery, Xuanming powder. There are many ingredients used in external use such as laryngology, Department of Traumatology, ophthalmology and so on.
At present, most enterprises use a chemical synthetic borneol to simulate the main characteristics of natural borneol instead of the use of synthetic borneol is made from turpentine and acid, alkali, catalysts and other chemicals through a series of chemical reactions, which contain isoborneol, heavy metals and arsenic salts and other substances, odor, and isoborneol to human beings The body is harmful, while the natural borneol is fragrant.
Efficacy and application of natural borneol (dextran borneol) in cosmetology and skin care
Natural borneol, formerly known as borneol, also known as dextroborneol, is mainly processed from fresh branches and leaves of camphor. Natural borneol has antibacterial, anti-inflammatory, analgesic, promoting transdermal absorption and other effects, has a wide range of applications in medicine, fragrances, cosmetics and skin care
3. Pharmacological action of natural borneol
Anti-inflammatory and analgesic effects
The results showed that the compound Jiujie tea cream containing natural borneol could significantly inhibit the auricle swelling induced by xylene in mice, and significantly reduce the number of writhing induced by acetic acid in mice after continuous administration. The skin irritation test showed that the compound Jiujie tea cream containing natural borneol had no irritation to normal skin and injured skin. Studies have shown that the efficacy of Xiaozhong Zhitong Powder combined with natural borneol in the treatment of acute gouty arthritis is significantly higher than that of Xiaozhong Zhitong Powder alone. It also contains natural borneol in oral ulcer powder, which can relieve ulcer inflammation and relieve pain.
Natural borneol has obvious antibacterial effect on many kinds of bacteria. It can obviously inhibit pathogenic bacteria and has a good inhibitory effect on fungi. Studies have shown that natural borneol combined with commonly used antibiotics can improve the antibacterial effect of antibiotics.
2.3 promoting the percutaneous absorption of drugs.
Natural borneol is a natural penetration enhancer. It was found that borneol could significantly down-regulate the expression of ABC transporter on the membrane of HepG2 cells and increase the permeability of HepG2 cells. It was found that the mechanism of osmotic enhancement depended on the concentration of natural borneol. At low concentrations, the lipid bilayer system maintained a bilayer structure, and natural borneol was added to loosen the lipid bilayer and improve drug permeation. The "pull" effect of natural borneol also improves drug penetration. At high concentrations, natural borneol leads to water pores and long-lived reverse micelles, which increases the possibility of other hydrophobic or hydrophilic drugs passing through the cuticle.
Increase eye surface humidity
Natural borneol is a compound widely used in ophthalmic preparations. Studies have shown that borneol can activate cold transient receptor potential M8 channels and moderately increase ocular surface humidity, suggesting that borneol is an active compound in ophthalmic preparations and is particularly useful in the treatment of dry eye syndrome.
4. The effectiveness of natural borneol in cosmetics
Based on the pharmacological characteristics of natural borneol, such as antimicrobial, analgesic and penetration promoting, natural borneol cosmetics such as floral dew, soap, bath lotion, facial mask, eye patch, acne removing, freckle removing and scar removing were developed on the market.
Acne skin care
Acne is a chronic inflammatory skin disease. It is a skin lesion. More often than not, it has a great impact on youngsters' psychology and life. Chinese medicine believes that the cause of the disease is hot and dry, oily food, endocrine disorders and so on. Studies have shown that natural borneol can promote the absorption of drugs by loosening the lipid layer, clearing away heat, clearing away heat and detoxification, and so on. Therefore, for the treatment of excessive lipid secretion diseases such as acne, clinical treatment formula contains natural borneol, can enhance the penetration of other drugs. Natural borneol facial mask cream and other cosmetics can play an antimicrobial and toxic effect, improve the metabolism of facial cortex, acne skin has a better effect.
Burn skin care
Infections and scars from burns and scalds are a big headache for beauty lovers. Prompt wound healing and prevention of infection are the first principles for treating burns. Modern pharmacological studies have shown that borneol can promote the regeneration of granulation tissue and epidermal cells, and has a strong wound healing effect. For example, there is natural borneol in the formulation of the detoxicating Shengji powder after wound healing.
Natural borneol can remove toxin and expel pus, restrain sores, promote the growth of granulation tissue, eliminate inflammation, promote ulcer healing, and achieve the goal of cure. Natural borneol cosmetics have the efficacy of disinfecting and promoting wound healing on special skin such as burn scars and acne scars.
Skin care of hormone dependent dermatitis
Hormone-dependent dermatitis is a dermatitis caused by repeated and improper use of hormone drugs for a long time, which seriously affects the appearance of patients. Natural borneol has inhibitory effects on bacteria and fungi, with little irritation and strong wound healing. In this study, zinc borate borneol ointment containing boric acid, zinc oxide and natural borneol was selected as a therapeutic drug for hormone-dependent dermatitis. 98 patients were treated with good results. Natural borneol cosmetics will play a very good role in skin care of patients with hormone dependent dermatitis.
Eczema skin care
Eczema is a kind of skin inflammation accompanied by severe itching, which is easy to recur and seriously affects the normal life of patients. Traditional Chinese medicine believes that the disease is caused by damp toxin infusion soaking the skin, so the treatment is mainly to clear away heat and detoxify, cool blood and dry damp. Natural borneol has the function of inducing orifices and dispersing stagnation of fire, so it can play a role in the treatment of eczema.
For example, Chen Yongfeng and other homemade purple yellow ointment contains natural borneol, in the prevention of infantile eczema treatment, has achieved better clinical efficacy. Natural borneol cosmetics are applied to skin care of patients with eczema.
Dry eye care
Dry eye disease refers to the stability of the tear film of the eye, accompanied by eye discomfort and (or) ocular surface tissue lesions characteristics of a variety of diseases. Natural borneol can increase ocular surface humidity, according to this mechanism, the clinical use of natural borneol eye drops in the treatment of dry eye. In addition, natural borneol can change part of the cornea structure, also can improve the blood-eye barrier permeability, promote the penetration of eye diseases drugs through the cornea into the eye, so natural borneol is widely used in a variety of ophthalmic preparations. Eye care cosmetics with natural borneol have similar efficacy.
The effectiveness of natural borneol in daily chemical products
With the improvement of human living standards, the types of daily chemical products are also increasing. Based on the characteristics of natural borneol, such as clearing away heat and detoxification, promoting transdermal absorption, natural borneol products with certain efficacy appear on the market. For example, "refreshing and refreshing essential oil" contains natural borneol, mint leaves and lavender, with refreshing and refreshing functions, can relieve mental tension, and raw materials are natural, no side effects, suitable for people to use at rest; "liquid wound protection film" by natural borneol, Panax notoginseng extract, turmeric extract and other mixture and Cheng, has good hemostatic, analgesic, antipruritic, bacteriostatic and waterproof effect; "multi-purpose wet towel" the main ingredients are natural borneol, mint essence, with refreshing, anti-inflammatory, anti-itching and anti-carsickness effect, to reduce fatigue driving hidden dangers, improve learning efficiency has great help; "non-stimulating children drive mosquitoes." The main ingredients of Antipruritic Dew are natural borneol and Geranium (mosquito repellent grass) essential oil. The natural mosquito repellent, antipruritic and bactericidal properties of Antipruritic Dew prevent skin damage caused by the use of chemical synthetic insect repellents and antipruritic products.
At present, based on cost considerations, most of the daily chemical products use synthetic borneol, synthetic borneol contains isoborneol and other ingredients, and daily chemical products as long-term contact skin care products, synthetic borneol safety is questioned. Natural borneol instead of synthetic borneol is the future development trend of this kind of products.
5. Storage of Natural Borneol
Keep it in a cool, dry place, away from light and heat
Shelf life: 2 years
Package: Double-layer plastic bag for internal package and cardboard bucket for outer package (25kg/drum)