Metaraminol Bitartrate 33402-03-8

99% up by HPLC

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Product Information

Product name	Metaraminol Bitartrate
CAS No.	33402-03-8
Molecular Formula	C9H13NO2.C4H6O6
Molecular Weight	317.29
Molecular Structure
Quality Standard	99% up by HPLC
Appearance	White crystalline powder

COA

ANALYSIS	SPECIFICATION	RESULTS
Appearance	White crystalline powder	Complies
Solubility	Freely soluble in water, sparingly soluble in ethanol(96%); practically insoluble in ether.	Complies
Identification	A. In the test for Related substances the principal spot obtained with solution(2) corresponds to that obtained with solution(4).	Complies
	B. An intense blue colour is produced.	Complies
	C. A mauve colour is immediately produced in the toluene layer.	Complies
pH	3.2-3.5	3.35
Phenones	Absorbance at 310nm,not more than 0.2,calculated with reference to the dried substance.	Complies
Related substances	Any impurity ≤0.5%	Complies
Loss on drying	≤0.5%	0.07%
Sulphated Ash	≤0.1%	0.01%
Heavy metals	≤ 20ppm	Complies
Sulphated Ash	≤0.1%	0.01%
Micorbial count	≤ 100cfu/g	Complies
Assay (dried substance)	99.0% - 101.0%	100.10%
Conclusion	The product complies with specification.

Usage

What is Metaraminol Bitartrate?

Metaraminol Bitartrate injection is an α1 and α2 adrenergic receptor agonist. Metaraminol Bitartrate also has a certain stimulating effect on the β1 receptor of the heart. It can constrict blood vessels, reflexively slow down the heart rate, and increase the contractility of the myocardium. Metaraminol Bitartrate has certain effects in increasing blood pressure.

Metaraminol Bitartrate injection is used to prevent and treat hypotension caused by sepsis or cardiogenic shock. It can also be used to prevent and treat shock caused by drug allergies or surgical complications, bleeding, brain trauma or brain tumors, etc. Induced hypotension, this drug can be used as an auxiliary symptomatic treatment. It is also suitable for preventing and treating acute hypotension during neuraxial anesthesia.