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Prostaglandin Series

Lubiprostone 333963-40-9

Lubiprostone 333963-40-9

99% up by HPLC,for R&D use only
  • Product Details

Product Information


Product name

Lubiprostone

CAS No.

333963-40-9

Molecular Formula

C20H32F2O5

Molecular Weight

390.46

Molecular Structure

Quality Standard

99% up by HPLC, for R&D use only

Appearance

White powder


COA of Lubiprostone


Items

Standards

Results

Appearance

White crystals or crystalline powder, odorless

Complies

Identification

By IR

Complies

By HPLC

Complies

Water Content

≤ 0.50%

0.22%

Heavy Metals

≤ 10ppm

Complies

Residual Solvent

n-Hexane: ≤ 290ppm

ND

Ethyl acetate: ≤ 5000ppm

0.12%

Related Substances                        

Total impurities: ≤1.00%

0.04%

Purity(HPLC)

≥ 99.0%

99.96%

Reference Standard

In-house Standard

Conclusion

The product complied to In-house standard.




Usage


Function of Lubiprostone

Lubiprostone is a limited chloride channel activator, which can selectively activate the type 2 chloride channel (CIC-2) located on the luminal cell membrane of the epithelial tip of the gastrointestinal tract to increase the secretion of intestinal juice and intestinal motility, thereby Increase bowel movements, reduce the symptoms of chronic idiopathic constipation, and do not change the concentration of sodium and potassium in the plasma.


Application of Lubiprostone


Adult chronic idiopathic constipation, constipation-type irritable bowel syndrome (only for female patients over 18 years old);

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