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Prostaglandin Series

LATANOPROST 130209-82-4

LATANOPROST 130209-82-4

99% up
  • Product Details

Product Information


Product name

Latanoprost

Molecular Formula

C26H40O5

Molecular Weight

432.59

CAS No.

130209-82-4

Quality Standard

99% up, medical grade

Appearance

Light yellow oil


COA of Latanoporst


TESTS

SPECIFICATIONS

RESULTS

Description

Colorless or light yellow oil

Light yellow oil

Identification

A: IR

B: The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard solution, as obtained in the assay

Complies

Water

NMT 2.0%

0.05%

Optical rotation

+31°+38°

+35.2°

Residue on ignition

NMT 0.5%

0.05%

Related substances (HPLC)

Isopropyl

Dipheny lphosphorylpentanoate

NMT0.1%

0.06%

Related compound B

NMT0.5%

0.09%

Related compound A

NMT3.5%

N.D

Any unspecified impurity

NMT0.1%

0.06%

Total other impurities

NMT0.5%

0.08%

Related Compound E

NMT0.2%

0.02%

Residue

Solvent

n-Hexane

NMT0.029%

Not detected

Ethanol

NMT0.5%

0.15%

Methanol

NMT0.3%

Not detected

Isopropanol

NMT0.5%

Not detected

Assay

94.0%~102.0%

99.77%

Conclusion: The product complies as per above specification.


Usage


Function of Latanoprost

Latanoprost is a new type of phenyl substituted prostaglandin F2α, which is a selective F2α receptor agonist. It is an inactive substance that can quickly penetrate into the cornea and can be hydrolyzed into active free acids in the cornea and plasma. It can increase the outflow of aqueous humor through the corneal layer, and the amount of medication is small, but promotes the outflow of aqueous humor. This product can also smooth the trabecular meshwork structure of the glaucoma patients that are usually blocked.


Latanoprost is a new class of ocular hypotensive drugs developed in recent years and gradually applied to the clinic. Unlike other anti-glaucoma drugs, this product does not change the flow coefficient of the aqueous humor, the production of aqueous humor, and suprascleral venous pressure, but reduces the intraocular pressure by increasing the waterproofing from the uveal scleral passage and outflow.

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