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Emtricitabine 143491-57-0

Emtricitabine 143491-57-0

99% up, DMF, FDA (zero defect)
  • Product Details

Product Information


Product name

Emtricitabine

CAS No.

143491-57-0

Molecular Formula

C8H10FN3O3S

Molecular Weight

247.247

Quality Standard

98% up, Medicine Grade

Appearance

White powder


COA of Nonapeptide-1


TEST

SPECIFICATION

RESULTS

Appearance

White to off-white powder

White powder

Identification

By chiral HPLC: the retention time of the main peak corresponds within 2.0% to that of the cis-(-)-EMTB reference standard

< 0.1%

Conforms

 

By IR: Consistent with the reference standard

Conforms 

Clarity of solution (1% w/v in water)

  Clear, essentially free of visible particles

Conforms

Water Content

NMT 0.5%

< 0.1%

Heavy Metals as lead

NMT 20 ppm

< 10 ppm

Residue on ignition

NMT 0.2%

0.1%

Bulk density

Report data

0.20 g/mL

Particle size by laser light scattering

d50 30

24

d90: 45~75

51

Residual solvent

Methanol 0.20%

ND

Isopropyl acetate 0.20%

ND

l-propanol 1.00%

0.05

Any unspecified solvent 0.10 or the premitted daily exposure specified by ICH Q3C

ND

EMTB-Dioxolane

0.70%

ND

EMTB-Carboxylic acid

0.50%

ND

EMTB-Disulfide

0.30%

ND

Emtb sulfoxides

0.15%

0.05%

Any unspecified impurity by HPLC

0.10%

Trace

Total impurities by

1.0%

0.1%

Assay by HPLC

98.0~102.0 (Dried basis)

100.1

98.0~102.0 (Anhydrous basis)

100.1

Drug content factor(Report data)

0.999

cis-(-)chiral purity by HPLC(%)

cis-(-)-EMTB 98.5

100.0

cis-(+)-EMTB (report data)

Trace

trans-(-)-EMTB (report data)

ND

trans-(+)-EMTB (report data)

ND

CONCLUSION

LOT MEETS SPECIFICATION


Usage

Function of Emtricitabine


Emtricitabine is a new type of nucleoside reverse transcriptase inhibitor that has antiviral activity against HIV-1, HIV-2 and HBV. This product is phosphorylated into cellular active 5'-triphosphate after oral administration. The 5'-triphosphate enters the viral DNA backbone and binds to the backbone, resulting in chain termination, thereby inhibiting HIV-1 reverse transcriptase and HBV DNA polymerase activity.


Emtricitabine does not affect the liver microsomal enzyme P450 enzyme system, and does not produce drug interactions mediated by it. It is used in combination with tenofovir, indinavir, famciclovir, and stanvudine, with almost no pharmacokinetics influences.

Our advantages of Emtricitabine (CAS: 143491-57-0)  :
1. Quality: 99% up, full test report. 

2. Documents: DMF, our facotory pass FDA audit with Zero defect. passing MCC in South African,
3. Large capacity & stock :80MT per year with 1000kg in stock for prompt shipment
4. Better payment terms : We can make use of Export Credit Insurance after confirming yr credit report accepted by Sinosure.

5. Various shipping ways for your choice : by air./ by sea / by courier (DHL/FedEx).

6. we also provide TDF, TAF, Efavirenz, that used togher with Emtritabine as the Compound Preparation to treat HIV.

 

The main Compound Preparation:

TDF+Emtricitabine and TDF+Emtricitabine+Efavirenz.


Other anti-virus products.

 

1. Oseltamivir phosphate 99%

2. Tenofivir Disoproxil Fumarate 99% 

3. Lamivudine USP

4. Zidovudine USP
5. Lopinavir  USP

6. Ritonavir USP

7. Remdesivir USP

8. Abacavir sulfate USP

9. Efavirenz

10. TAF

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Send A Message
Send A Message
If you are interested in our products and want to know more details,please leave a message here,we will reply you as soon as we can.

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