Empagliflozin Intermediate/ (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran/ 915095-89-5

99% up by HPLC, total impurity < 0.1%

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Product name	Empagliflozin Intermediate (3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran
Synonyms	Empagliflozin int3; Empagliflozin-7; Empagliflozin Bromo Impurity; (S)-4-bromo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)-benzene; 3-[4-[(5-broMo-2-chlorophenyl)Methyl]phenoxy]tetrahydro-; (3S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydro-furan; (3S)-3-[4-[(5-bromo-2-chlorophenyl)methyl]phenoxy]oxolane 915095-89-5
CAS No.	915095-89-5
Molecular Formula	C17H16BrClO2
Molecular Weight	367.66
Molecular Structure
Quality Standard	99% up by HPLC
Appearance	White to off-white powder

3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran Chemical Properties
Melting point	49-51°C
Boiling point	459.1±45.0 °C(Predicted)
density	1.431±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid

Usage

(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.