NMN (β-Nicotinamide Mononucleotide； Beta-Nicotinamide Mononucleotide) is a substance inherent in the human body and has important physiological functions for human cells. In the human body, NMN is the precursor for the synthesis of NAD+, and its physiological function is mainly reflected by increasing the level of NAD+. NAD is an important coenzyme for cell energy conversion, but it will decrease with age. The decrease of NAD will affect physiological functions. Use NMN The drug can increase NAD+ levels, thereby delaying aging. NMN belongs to the category of vitamin B derivatives. It is widely involved in many biochemical reactions in the human body. There are about 4000 kinds of enzymes in the body involved in metabolism. Supplementing NMN can supplement the enzymes required by 2000 kinds of organs. Therefore, NMN is closely related to immunity and metabolism.

The principle of NMN's efficacy is because NMN has membrane transporters on the surface of certain cells, which can directly transfer NMN into cells. At the beginning of 2019, a paper on nature metabolism confirmed this idea. The article found that there is a NMN specific transporter in the small intestine, called Slc12a8, which is an amino acid and polyamine transporter with high selectivity for NMN. The concentration of Slc12a8 in the small intestine is 10-100 times that of other organs, so The absorption rate is very high. The small intestine is actually a dedicated channel for NMN.