Nintedanib intermediate 262368-30-9

Basic information of Nintedanib intermediate 262368-30-9 :

Name	Nintedanib intermediate 262368-30-9 N-(4-Aminophenyl)-N,4-dimethyl-1-piperazineacetamide
Appearance:	White powder
CAS NO.	262368-30-9
MF	C14H22N4O
MW	262.35
Grade Standard	98% by HPLC
Package Size	25kg/drum

Use of Nintedanib intermediate 262368-30-9:

Nintedanib intermediate 262368-30-9 is a key intermediate for Nintedanib .

Nidanib targets platelet-derived growth factor receptors (PDGF alpha and beta), fibroblast growth factor receptor (FGFR1-3), vascular endothelial growth factor receptor (VEGFR1-3), and adenosine triphosphate with these receptors. (ATP) competitive binding of binding sites, blocking the signaling pathway of fibrosis, inhibiting the spread, metastasis and transformation of fibroblasts, thereby slowing the progression of idiopathic pulmonary fibrosis (IPF) disease.

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