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Linagliptin 668270-12-0 Linagliptin 668270-12-0

Linagliptin 668270-12-0
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Basic information of Linagliptin:

Name

Linagliptin

Alias

8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione

CAS NO.

668270-12-0

Molecular Formula

C25H28N8O2

Molecular Weight

472.54

Grade Standard

Medicine grade  / 99% min / GMP application / PMDA / DMF

Package Size

25kg/drum

Storage:

Keep in a well-closed container, protected from light and stored at a temperature of 2 to 8


Use of Linagliptin:

Linagliptin is used to control of blood glucose levels in people with type 2 diabetes by combining diet and exercise. Linagliptin controls glycemic in patients by inhibiting dipeptidyl peptidase-4 (DPP-4).

Compared with other DPP-4 inhibitors, the main advantages of linagliptin are: excellent renal safety and effective reduction of glycated hemoglobin. Lilacitin is mainly excreted in the form of a prototype, and after oral administration, the amount of renal excretion is only 5% of the dose, and even if administered intravenously, only 30.8% is excreted by the kidney, so the patient receiving the treatment does not need Regular examination of liver and kidney function and dose adjustment, all patients can be fixed doses, easy to prescribe.

COA of Linagliptin:

Items

 

Specification

 

Result

 

Assay

 

≥98.5%

 

99.77%

 

Appearance

 

White to light yellow powder

 

Light yellow powder

Loss on drying

≤0.5%

0.38%

Residue on drying

≤0.1%

0.07%

Single impurity

≤0.5%

0.08%

Total impurity

≤1.5%

0.23%



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MORE_DETAIL Linagliptin 668270-12-0

Basic information of Linagliptin:

Name

Linagliptin

Alias

8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione

CAS NO.

668270-12-0

Molecular Formula

C25H28N8O2

Molecular Weight

472.54

Grade Standard

Medicine grade  / 99% min / GMP application / PMDA / DMF

Package Size

25kg/drum

Storage:

Keep in a well-closed container, protected from light and stored at a temperature of 2 to 8


Use of Linagliptin:

Linagliptin is used to control of blood glucose levels in people with type 2 diabetes by combining diet and exercise. Linagliptin controls glycemic in patients by inhibiting dipeptidyl peptidase-4 (DPP-4).

Compared with other DPP-4 inhibitors, the main advantages of linagliptin are: excellent renal safety and effective reduction of glycated hemoglobin. Lilacitin is mainly excreted in the form of a prototype, and after oral administration, the amount of renal excretion is only 5% of the dose, and even if administered intravenously, only 30.8% is excreted by the kidney, so the patient receiving the treatment does not need Regular examination of liver and kidney function and dose adjustment, all patients can be fixed doses, easy to prescribe.

COA of Linagliptin:

Items

 

Specification

 

Result

 

Assay

 

≥98.5%

 

99.77%

 

Appearance

 

White to light yellow powder

 

Light yellow powder

Loss on drying

≤0.5%

0.38%

Residue on drying

≤0.1%

0.07%

Single impurity

≤0.5%

0.08%

Total impurity

≤1.5%

0.23%


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