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Granisetron Hcl 107007-88-9 Granisetron Hcl 107007-88-9

Granisetron Hcl 107007-88-9
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1.Basic information of Granisetron Hcl 107007-88-9:

Product name

Granisetron Hcl / Granisetronhydrochloride

CAS No.

107007-88-9

M.F.

C18H25CIN40

Appearance

White powder

Assay

97.0% - 102%

Ph

4.0 - 6.5

Standard

EP / BP / USP

Certificate

GMP / DMF


2.Usage of Granisetron Hcl 107007-88-9 :


Granisetron hydrochloride is a highly selective serotonin 3 (5-HT3) receptor antagonist with good preventive and therapeutic effects on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. Radiotherapy, chemotherapy and surgery can cause 5-HT release from intestinal chromaffin cells. 5-HT activates the 5-HT3 receptor in the central or vagal nerve terminals and causes vomiting reflex. The mechanism of this product to control nausea and vomiting is to inhibit the occurrence of nausea and vomiting by antagonizing the 5-HT3 receptor in the central chemosensory region and peripheral vagal nerve endings. This product has high selectivity and no adverse reactions such as extrapyramidal reaction and excessive sedation. Common side effects are headache, burnout, fever, constipation and gastrointestinal dysfunction, and occasionally transient asymptomatic liver transaminase increases. The above reaction is mild and requires no special treatment.

3.COA of Granisetron Hcl 107007-88-9 :

COA of Granisetron Hcl 107007-88-9


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MORE_DETAIL Granisetron Hcl 107007-88-9

1.Basic information of Granisetron Hcl 107007-88-9:

Product name

Granisetron Hcl / Granisetronhydrochloride

CAS No.

107007-88-9

M.F.

C18H25CIN40

Appearance

White powder

Assay

97.0% - 102%

Ph

4.0 - 6.5

Standard

EP / BP / USP

Certificate

GMP / DMF


2.Usage of Granisetron Hcl 107007-88-9 :


Granisetron hydrochloride is a highly selective serotonin 3 (5-HT3) receptor antagonist with good preventive and therapeutic effects on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. Radiotherapy, chemotherapy and surgery can cause 5-HT release from intestinal chromaffin cells. 5-HT activates the 5-HT3 receptor in the central or vagal nerve terminals and causes vomiting reflex. The mechanism of this product to control nausea and vomiting is to inhibit the occurrence of nausea and vomiting by antagonizing the 5-HT3 receptor in the central chemosensory region and peripheral vagal nerve endings. This product has high selectivity and no adverse reactions such as extrapyramidal reaction and excessive sedation. Common side effects are headache, burnout, fever, constipation and gastrointestinal dysfunction, and occasionally transient asymptomatic liver transaminase increases. The above reaction is mild and requires no special treatment.

3.COA of Granisetron Hcl 107007-88-9 :

COA of Granisetron Hcl 107007-88-9

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