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Product Information |
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Product name |
Capecitabine |
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Molecular Formula |
C15H22FN3O6 |
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Molecular Weight |
359.35 |
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CAS No. |
154361-50-9 |
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Quality Standard |
USP34, medical grade |
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Appearance |
White powder |
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COA of CAPECITABINE |
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Items |
Specifications |
Results |
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Apperance |
White or off-white crystalline powder |
White crystalline powder |
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Identification |
The spectrum of the sample corresponds to that of RS |
Meets the requirements |
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The retention time of the major peak of the test solution corresponds to that of the RS |
Meets the requirements |
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Specific Rotation |
+96.0°~+100.0° |
+98.1° |
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Water |
≤0.3% |
0.01% |
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Heavy Metals |
≤20ppm |
<20ppm |
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(as Pb) |
||
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Residue on ignition |
≤0.1% |
0.02% |
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Assay |
98.0%~102.0% |
99.70% |
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|
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Usage |
Function of Capecitabine
Capecitabine is rapidly absorbed through the intestinal mucosa after oral administration, and then converted into an inactive intermediate 5'-deoxy-5'fluorocytidine in the liver by carboxylesterase, and then decellularized by the liver and tumor The action of ammonia enzyme is converted into 5'-deoxy-5 'fluorouridine, and finally catalyzed by thymidine phosphorylase into fluorouracil (5-FU) in tumor tissue.
Clinical studies have shown that the concentration of 5-FU in tumor tissue after oral administration of this product is significantly higher than blood and muscle levels. The curative effect on various animal tumors is significantly higher than that of 5-FU. This product has a synergistic effect with a variety of anti-tumor drugs.
*Products under the patent are only for R&D use