Heparin sodium 9041-08-1

99% up by HPLC, BP, USP

99% up by HPLC, total impurities < 0.1%, single impurity < 0.05%

99% up, Cosmetic grade/ Tech grade

Product Information Product name Isavuconazole CAS No. 241479-67-4 Molecular Formula C22H17F2N5OS Molecular Weight 437.473 Molecular Structure Quality Standard 98% up by HPLC Appearance White to yellow powder COA of Isavuconazole ITEMS STANDARDS RESULTS Appearance White to yellow powder Conforms Identification The peak position of T001-M9 in the test solution was the same as that in the related solution. Conforms Solubility Practically insoluble in water，soluble Conforms Melting point 120℃~126℃ 121.5℃~123.0℃ Specific Optical Rotation [α]D20：-25.0°~-34.0° -29.1° Related substances Any single impurity≤0.5% 0.17% Total impurity ≤1.0% 0.23% Loss on drying ≤1.0% 0.09% Assay ≥ 98% 99.77% Conclusion The above items have been tested according with the Enterprise Standard for the product，the results comply with Specifications . Usage Isavuconazole is a new type of triazole antifungal drug. On the basis of retaining the potent anti-Candida activity of the first-generation triazole drugs, it has enhanced the activity against filamentous fungal infection and is a broad-spectrum antifungal drug. Compared with other azoles, the special molecular structure of isavuconazole sulfate (containing 2 chiral centers) enables the orientation of the triazole ring to engage with the binding pocket of the fungal CYP51 protein, thus giving it a broader antifungal spectrum , including fungi resistant to azoles (such as itraconazole, voriconazole, and posaconazole), have good antibacterial activity. *Products under the patent are only for R&D use

Product Information Product name 2-Hydroxy-3-nitro-(1, 1-biphenyl)-3-carboxylic acid CAS No. 376591-95-6 Molecular Formula C13H9NO5 Molecular Weight 259.218 Molecular Structure Quality Standard 98% up by HPLC Appearance Slightly yellow to yellow powder COA Test Items Specification Test Results Appearance Slightly yellow to yellow powder Yellow powder MS The molecular weight should be consistent with the molecular weight of the target compound. The molecular weight should be consistent with the molecular weight of the target compound. Related substance Largest single impurity ≤0.2% 0.18% Total impurities ≤2.0% 0.34% Purity ≥ 98.0% 99.7% Residue on ignition ≤0.2% 0.08% Loss on drying ≤1.0% 0.02% Residue solvents Methanol ≤0.3% 0.01% Acetone ≤0.5% ND Dichloromethane ≤0.06% ND Heptane ≤0.5% ND Acetic acid ≤0.5% ND Conclusion The product conforms to the requirements of Enterprise standard.

99% up, USP32

99.0% up by HPLC

98% up, Cosmetic Grade