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  • Glucosylrutin
    Product Information   Product name α-Glucosylrutin; alpha-Glucosylrutin CAS No. 130603-71-3 Molecular Formula C33H40O21 Molecular Weight 432.59 Appearance Yellow to yellowish brown powder   COA   Test Items Specifications Results CHARACTERS      - Appearance Yellow to yellowish brown powder. Yellow powder.  - Solubility Freely soluble in water and methanol, slightly soluble in ethanol (96%). Conforms IDENTIFICATION      A. Infrared absorption spectrophotometry Comparison: Enzymatically Modified Rutin RS. Conforms  B. UV/Vis absorption spectrophotometry UV spectrum of test solution should have a absorption maxima at wavelengths of approximately 255nm and 350nm. Conforms  C. Examine the chromatograms obtained in the Assay by HPLC The principal peak in the chromatogram obtained with the test solution is similar in retention time to the principal peak in the chromatogram obtained with reference solution. Conforms TESTS      - Appearance and colour of solution, 1.0g/10mL water Light yellow to yellow clear solution Light yellow clear solution  - Loss on drying , 105℃×3h ≤ 5.0 % 2.5 %  - Sulphated ash ≤ 0.60 % 0.49 %  - Heavy metals, as Pb ≤ 20 ppm < 20 ppm  - Elemental impurities ICH Q3D Conform     -- Arsenic (As) ≤ 1.5 ppm < 0.01 ppm     -- Cadmium (Cd) ≤ 0.5 ppm < 0.01 ppm     -- Lead (Pb) ≤ 0.5 ppm < 0.05 ppm     -- Mercury (Hg) ≤ 3.0 ppm < 0.01 ppm ASSAY, on dried substance      - Quercetin glycosides, by HPLC ≥ 70.0 % 90.1 %  - α-Monoglucosylrutin, by HPLC   ≥ 50.0 % 69.5 %  - As rutin, by UV/Vis ≥ 60.0 % 82.6 % PARTICLE-SIZE DISTRIBUTION Not less than 97% of the powder by mass passes through a number 180 sieve (80 mesh sieve). Not less than 97% of the powder by mass passes through a number 180 sieve (80 mesh sieve). RESIDUAL SOLVENTS ICH Q3C Conform  - Methanol ≤ 3000 ppm 14 ppm  - Ethanol ≤ 5000 ppm < 10 ppm MICROBIOLOGICAL TESTS      - Total aerobic microbial count ≤ 103 CFU/g < 102 CFU/g  - Total yeasts and moulds count ≤ 102 CFU/g < 10 CFU/g  - Escherichia Coli Absent in 1 g Absent in 1 g CONCLUSION: THE TEST RESULTS CONFORM TO THE SPECIFICATION 50350-01.   Usage   Core Efficacy of α-Glucosylrutin α-Glucosylrutin, produced via enzymatic modification, surpasses standard rutin by fundamentally addressing its two major inherent deficiencies: extremely poor water solubility and relatively weak stability. The introduction of a hydrophilic glucosyl group results in a qualitative leap in its biological efficacy.   1. Exceptional Antioxidant Activity α-Glucosylrutin retains rutin's potent free radical-scavenging capacity and synergizes with vitamins C and E to form an "antioxidant network," providing multi-layered protection. Key Enhancement:Due to its excellent water solubility and cellular permeability, its intracellular antioxidant effect far exceeds that of rutin, enabling it to protect cells from oxidative stress damage more effectively. 2. Potent Photoprotective Effects (A Star Function) UV Absorption: Capable of absorbing UVB and partial UVA, acting as a physical sunscreen agent. Reduction of Photodamage: This represents its core application. It significantly inhibits UV-induced reactive oxygen species generation, matrix metalloproteinase (MMP) activation, and inflammatory factor release. This addresses the root causes to prevent photoaging, reduce collagen degradation, and inhibit pigmentation. Stabilization of Vitamin C: In skincare formulations, it markedly enhances the stability of L-ascorbic acid, preventing its oxidation and inactivation, making it an ideal partner in "Vitamin C morning routine" products. 3. Anti-Inflammatory and Soothing Properties By inhibiting inflammatory pathways such as NF-κB, it effectively mitigates skin irritation, redness, and inflammatory responses, making it suitable for sensitive skin care and reparative products. 4. Enhancement of Vascular Strength and Microcirculation It inherits rutin's ability to improve capillary fragility and enhance vascular elasticity. In oral supplements, it is used to address conditions like venous insufficiency and edema.

    Tags : 130603-71-3 α-Glucosylrutin alpha-Glucosylrutin Glucosylrutin Enzymatically Modified Rutin Rutin derivatives​

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