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Product name

Echinacea Purpurea Extract ; Echinacea Extract

Specification

Phenols ≥ 4%

Loss on drying

≤5.0%

Extraction solvent

Ethanol & water

Pesticide Residue

Complies

Quality Standard

USP42


COA of Echinacea Purpurea Extract


Items

Specification

Results

Appearance

Yellow-green to deep yellow-green powder

Yellow-green powder

Identification

The retention time of the major peak in the sample solution corresponds to that of the chicoric acid peak in standard solution A, and the second mostprominent peak corresponds to that of the caftaric acid peak in standard solution B.

Complies

Loss on drying

Not more than 5.0%

3.8%

Elemental impurities

Arsenic not more than 1.0µg/g

--

Cadmium not more than 0.5µg/g

--

Lead not more than 5.0µg/g

--

Mercury not more than 1.0µg/g

--

Pesticide residue

Complies

--

Residual solvents

Ethanol should not more than 5000 ppm

--

Microbial limit test(MLT)

Total bacteria not more than 10000 cfu/g

Complies

Total yeasts and moulds not more than 1000 cfu/g

Complies

Escherichia coli. and salmonella absent

Complies

Assay

Contains Phenols(calculated as the total of caftaric acid, chicoric acid and chlorogenic acid) should not less than 4.0%, calculated on the anhydrous substance.

7.2%

Conclusion

The above materials are done based on USP42 and all the testing data meet the established specification.



Usage


Echinacea's main active ingredients, polyphenols, caffeic acid derivatives and polysaccharides have the following function -- Significantly improve immune system:

·         Antibiotics

·         Activation of tissue growth

·         Blood purification

·         Antiviral effect

·         Anti-oxidation and anti-free radical effect

·         Tumor inhibition

·         Inhibiting effect on hyaluronidase

·         Anti-inflammatory effect

·         Interferon-like effect


1. Immune stimulation

Inulin: plays a role by increasing the number of granulocytes and white blood cells, and increases the chemotaxis of monocytes and neutrophils.

Polysaccharide: the hydrocarbon receptors on the surface of T lymphocytes and macrophages produce immune stimulation, which can increase the phagocytosis ability of macrophages, and stimulate macrophages to increase the number of tumor necrosis factor, interferon, and white blood cell intermediation, which can destroy tumor cells.

Alkylamines and caffeic acid derivatives: lipophilic alkylamines can increase the phagocytic ability of macrophages.

Echinacea: increases the activity of non-specific T cells, produces interferon, promotes the secretion of lymphocytes, reduces t-helper cells, and reduces the ratio of t-helper cells to inhibitory factors.

2. Tissue renewal and anti-infection effect

Inhibiting hyaluronidase (hyaluronidase) can stimulate the growth of fibroblasts and the synthesis of glucosaminase, produce corticosterone and promote the secretion of adrenal cortical hormone.Polysaccharides have anti-infection effects.

3. Antibacterial effect

Echinacea and caffeic acid derivatives have weak antibacterial activity.

4. Antiviral effect

Can inhibit influenza, herpes and blistering viruses, antiviral activity is attributed to the inhibition of hyaluronidase, can block the cell surface of the virus receptor.


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