There was no cross-resistance of other antibiotics in the mupirocin
. Compared with other commonly used antibiotics in Department of Dermatology, Mupirocin Ointment maintained sensitivity to sensitive strains. So, can Mupirocin Ointment treat folliculitis?
The pathological cause of folliculitis is: the main pathogen of pyogenic disease is Staphylococcus. Low immune function, diabetes, poor skin hygiene, and scratching are all the inducements of this disease. In the follicles, the normal parasitism of acne vulgaris (PA), Malassezia furfur and Staphylococcus epidermidis, etc. When the free fatty acids increase, the Bacillus propionate cannot produce a sufficient enzyme to decompose the sebum, and the stagnant fatty acid causes the nonspecific inflammatory reaction around the hair follicle.
The mupirocin has a strong antibacterial activity for gram-positive coccus, especially for Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus pyogenes, which are related to skin infection. It is also effective for drug-resistant Staphylococcus aureus. Gram-negative bacteria that are sensitive to Mupirocin are Haemophilus influenza, Neisseria gonorrhoeae, etc. Moipirome inhibited the normal flora of the skin, such as Micrococcus, Corynebacterium and Propionibacterium, which had a congenital infection barrier. It has no inhibitory effect on Pseudomonas aeruginosa, anaerobic bacteria and fungi.
Therefore, Mupirocin Ointment can treat folliculitis. When Mupirocin Ointment is applied to the skin, its transdermal absorption is very small. After absorption, it is rapidly metabolized into inactive first acid and excreted by the kidneys. In clinical observation, blood routine, urine routine, liver function and renal function were not found abnormal, and no systemic toxicity was found. Short itching, prickle and burning sensation were mostly caused by sealing and matrix. Patients can be treated correctly under the guidance of professional doctors.