Effect Of Metoprolol Combined With Valsartan In Patients With Essential Hypertension
Recently, Armed Police Corps Hospital Specialist researchers published papers aimed at observing metoprolol combined valsartan treatment of hypertension on left ventricular hypertrophy and left ventricular diastolic function. Studies have shown that metoprolol combined with valsartan in the treatment of hypertension can reduce blood pressure, reduce left ventricular hypertrophy and improve left ventricular diastolic function. This article was published in the 12th issue of "Armed Police Medicine" in 2015.
A total of 180 hypertensive patients with left ventricular hypertrophy (LVH) undergoing echocardiography were selected and randomly divided into three groups: A, B and C, A group received metoprolol and valsartan, and group B received valsartan Treatment; C group metoprolol treatment; treatment were 1 year. Cardiac echocardiography was performed and left ventricular muscle mass and left ventricular mass index (LVMI) were calculated. Ambulatory blood pressure and electrocardiogram were measured 24 hours before and after treatment and compared between groups.
After treatment, the blood pressure decreased, left ventricular hypertrophy and left ventricular diastolic function were all shown to be effective (P <0.01), but the efficacy of group A was better than that of group B and C (P <0.01) From (136.8 ± 7.3) g / m2 to (127.7 ± 4.6) g / m2, left ventricular diastolic function increased.