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Advantages of Nifuratel Advantages of Nifuratel

Nifuratel powder can be quickly absorbed after oral administration and healthy volunteers can reach the maximum blood concentration of 9.48 μg/ml within 2 hours after taking 200 mg nifuratel powder orally, but its metabolism is also very rapid. Its half-time is only 2.75 hours, and its metabolites still had antibacterial activity.

In addition, Nifuratel powder has a big advantag - safety.

1. High-dose and long-term toxicological experiments ( Note: The oral dose for adult treatment is 8.57 mg/kg/day):

Experimental Animal Cycle Maximum Safe Dose
Rat 47 Days 150mg/kg/day
Dog 6 Months 100mg/kg/day


2. Reproductive / teratogenic toxicology experiment ( Note: The oral dose for adult treatment is 8.57 mg/kg/day):

Experimental Animal Experimental Contents Oral Dose Result
Rat Ability to produce sperm 450mg/kg No Effect
Mice Rat White Rabbit Teratogenicity 200mg/kg 200mg/kg 100mg/kg No Effect

3. There were more than 5000 clinical trials in the world, and 10% (about 500 cases) were selected as cases of illness. Nifuratel nystatin has achieved good results, at the same time, no serious adverse reactions were found.
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