Febuxostat 144060-53-7

99% up by HPLC, EDMF

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Product Details

Product Information

Product name	Febuxostat
CAS No.	144060-53-7
Molecular Formula	C16H16N2O3S
Molecular Weight	316.3748
Quality Standard	99% up by HPLC, EDMF
Appearance	White powder

COA of Febuxostat

ITEMS	SPECIFICATIONS	RESULTS
CHARACTERISTICS	A WHITE OR WHITE CRYSTALLINE POWDER	COMPLIES
IDENTIFICATION	POSITIVE	COMPLIES
SOLUBILITY OF SOLUTION AND COLOUR	COMPLIES	COMPLIES
ASSAY(BY HPLC)	98%~102%	99.7%
RELATED IMPURITIES	NMT0.1%	0.1%
LOSS ON DRYING	NMT0.5%	0.2%
RESIDUE ON IGNITION	NMT0.2%	0.05%
HEAVY METALS	NMT0.001%	NMT0.001%
CONCLUSION:THE PRODUCT COMPLIES WITH EDMF STANDARD.

Usage

Function of Febuxostat

The main effect of febuxostat is to promote uric acid excretion and inhibit uric acid production.

At present, the drugs for the treatment of elevated uric acid in my country mainly include two categories: 1. Drugs that promote the excretion of uric acid, such as benzbromarone; 2. Drugs that inhibit the production of uric acid, the most representative of which is allopurinol. Febuxostat is a new type of uric acid-lowering drug with a similar mechanism of action to allopurinol, mainly inhibiting xanthinase, thereby inhibiting the production of uric acid. At the same time, febuxostat has less side effects and has less impact on liver and kidney function, especially patients with moderate or lower renal insufficiency can use febuxostat with confidence. At the same time, patients can achieve a good therapeutic effect on gout by cooperating with diet and strict low-purine diet.