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Febuxostat 144060-53-7 Febuxostat 144060-53-7

Febuxostat 144060-53-7
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Basic information of Febuxostat 144060-53-7

Name

Febuxostat

Alias

2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid

CAS Number

144060-53-7

Molecular Formula

C16H16N2O3S

Molecular Weight

316.37

Quality Standard

In house(Form A, Form III, Form G)

Package Size

25kg/drum, according your requirement

Brief Introduction

Febuxostat (febuxostat) by Teijin has developed a new generation of xanthine oxidase inhibitor,
for the treatment of high uric acid disease (gout), 40 years ago, the structure and development
of xanthine oxidase inhibitor drug on clinical completely different, it is a new and efficient
non-purine selective inhibitor of xanthine oxidase. Xanthine oxidase is a key enzyme to promote the production of uric acid.

Usage of Febuxostat 144060-53-7

  • Treatment of high uric acid disease (gout)

COA of Febuxostat 144060-53-7

Crystal: Form A

SI.No.

Items

Specifications

Results

01

Appearance

White to off-white crystalline powder

Off-white crystalline powder

02

Identification

A: UV

B: HPLC

C: X-RD

Conforms

Conforms

Conforms

03

Related Substances(By HPLC)

Methanol: NMT 0.3%

Ethanol: NMT 0.5%

Formic acid: NMT 0.5%

DMF: NMT 0.088%

ND

ND

ND

ND

04

Loss on Drying

(At 105℃till constant weight)

Not more than 1.0%

0.26%

05

Residue on Ignition

Not more than 0.1%

0.06%

06

Related Substances(By HPLC)

Maximum single impurity: NMT 0.1%

Total impurities: NMT 0.5%

0.02%

0.02%

07

Heavy Metals

Not more than 20ppm

Conforms

08

Chlorides

Not more than 0.04%

Conforms

09

Assay(on dried basis)

Not more than 98.5%

100.4%

Remark

Crystal: A



MORE_DETAIL Febuxostat 144060-53-7

Basic information of Febuxostat 144060-53-7

Name

Febuxostat

Alias

2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid

CAS Number

144060-53-7

Molecular Formula

C16H16N2O3S

Molecular Weight

316.37

Quality Standard

In house(Form A, Form III, Form G)

Package Size

25kg/drum, according your requirement

Brief Introduction

Febuxostat (febuxostat) by Teijin has developed a new generation of xanthine oxidase inhibitor,
for the treatment of high uric acid disease (gout), 40 years ago, the structure and development
of xanthine oxidase inhibitor drug on clinical completely different, it is a new and efficient
non-purine selective inhibitor of xanthine oxidase. Xanthine oxidase is a key enzyme to promote the production of uric acid.

Usage of Febuxostat 144060-53-7

  • Treatment of high uric acid disease (gout)

COA of Febuxostat 144060-53-7

Crystal: Form A

SI.No.

Items

Specifications

Results

01

Appearance

White to off-white crystalline powder

Off-white crystalline powder

02

Identification

A: UV

B: HPLC

C: X-RD

Conforms

Conforms

Conforms

03

Related Substances(By HPLC)

Methanol: NMT 0.3%

Ethanol: NMT 0.5%

Formic acid: NMT 0.5%

DMF: NMT 0.088%

ND

ND

ND

ND

04

Loss on Drying

(At 105℃till constant weight)

Not more than 1.0%

0.26%

05

Residue on Ignition

Not more than 0.1%

0.06%

06

Related Substances(By HPLC)

Maximum single impurity: NMT 0.1%

Total impurities: NMT 0.5%

0.02%

0.02%

07

Heavy Metals

Not more than 20ppm

Conforms

08

Chlorides

Not more than 0.04%

Conforms

09

Assay(on dried basis)

Not more than 98.5%

100.4%

Remark

Crystal: A


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