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Whitening Effect of Glutathione Whitening Effect of Glutathione

Glutathione is a substance that is innate in the human body. In infants and young children, glutathione is highest in the body and decreases with age. In nature, it is mainly found in yeast, animal liver, muscle and blood cells, and some plants also contain high glutathione. Glutathione is composed of glutamic acid, cysteine, and glycine. A tripeptide containing a thiol group, abbreviated as GSH, is a combination of glutathione and sulfhydryl SH. Like some whitening substances such as tranexamic acid, it is mainly used for non-whitening in the early clinical practice. The core role of glutathione in the clinical detoxification, so it has a significant role in the purification of internal organs, such as repairing liver and kidney damage, excluding heavy metals in the body. It was subsequently discovered that glutathione has a whitening effect on the skin and enhances the skin.


Glutathione does interfere with the synthesis of melanin, and its mechanisms include:

1. Direct inhibition of tyrosinase activity.
2. Free radicals can activate tyrosinase, while glutathione can scavenge free radicals to inhibit tyrosinase activation.
3. Make the melanin synthesis pathway prone to brown melanin (rather than melanin that darkens the skin).

Therefore, in general, the primary task of preventing skin aging and skin deterioration is a reasonable working time and a healthy lifestyle. In addition, the body's necessary antioxidants are used to scavenge free radicals. The biggest external cause of skin darkening and staining is still sunlight. So sun protection is the primary job of keeping your skin white and flawless. The second is to inhibit the action of tyrosinase by scientific means, or to restore and block the melanin that has been produced. These are some of the ways in which modern science whitens skin.

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