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Prednisolone 50-24-8 Prednisolone  50-24-8

Prednisolone  50-24-8
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Basic information of Prednisolone 50-24-8

  • Product Name: Prednisolone
  • Molecular Formula: C21H28O5
  • Molecular Weight: 360.44
  • CAS No.: 50-24-8
  • Appearance: White crystalline powder
  • Specifications: EP8/USP38/BP2014

Usage of Prednisolone 50-24-8

  • It used for autoimmune disease and allergic disease.
  • Such as Collagenous diseases; rheumatoid arthritis; erythematosus; severe bronchial asthma.
  • Nephritic syndrome etc.

COA of Prednisolone 50-24-8

Items

Specifications

Results

Appearance

White or almost white crystalline powder

White crystalline powder

Identification

A;B

Meets test

Specific rotation

+97°~+103°

+99°

Chromatogram purity

Any peak≤1.0%

Only one peak>0.50%

Total≤2.0%

Epi-prednisolone<0.05%

Hydrocortisone: 0.79%

11-Deoxypredmosolone<0.05%

Other detected imputiry: RRT (0.81) 0.06%

Total: 0.85%

Loss on drying

≤0.5%

0.1%

Residue on ignition

Negligible

Negligible

Selenium

≤0.003%

<0.003%

Assay

97.0~102.0%

(on dried substance)

99.0%

Conclusion

It conforms to USP38

Residual solvents

Methanol≤700ppm

Methylene chloride≤600ppm

29ppm

507ppm

Micronized

≤15μm>80%;≤30μm>98%



MORE_DETAIL Prednisolone 50-24-8

Basic information of Prednisolone 50-24-8

  • Product Name: Prednisolone
  • Molecular Formula: C21H28O5
  • Molecular Weight: 360.44
  • CAS No.: 50-24-8
  • Appearance: White crystalline powder
  • Specifications: EP8/USP38/BP2014

Usage of Prednisolone 50-24-8

  • It used for autoimmune disease and allergic disease.
  • Such as Collagenous diseases; rheumatoid arthritis; erythematosus; severe bronchial asthma.
  • Nephritic syndrome etc.

COA of Prednisolone 50-24-8

Items

Specifications

Results

Appearance

White or almost white crystalline powder

White crystalline powder

Identification

A;B

Meets test

Specific rotation

+97°~+103°

+99°

Chromatogram purity

Any peak≤1.0%

Only one peak>0.50%

Total≤2.0%

Epi-prednisolone<0.05%

Hydrocortisone: 0.79%

11-Deoxypredmosolone<0.05%

Other detected imputiry: RRT (0.81) 0.06%

Total: 0.85%

Loss on drying

≤0.5%

0.1%

Residue on ignition

Negligible

Negligible

Selenium

≤0.003%

<0.003%

Assay

97.0~102.0%

(on dried substance)

99.0%

Conclusion

It conforms to USP38

Residual solvents

Methanol≤700ppm

Methylene chloride≤600ppm

29ppm

507ppm

Micronized

≤15μm>80%;≤30μm>98%


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