Sinoway Industrial Co., Ltd.

Paclitaxel 33069-62-4 Paclitaxel 33069-62-4

Paclitaxel 33069-62-4
Related Products
  • L-Glutathione Reduced (GSH) 70-18-8

    L-Glutathione ReducedBasic information of L-Glutathione Reduced:Product name: L-Glutathione ReducedMolecular Formula : C20H32N6O12S2Molecular Weight: 612.63CAS No.:70-18-8ENIECE No: 200-725-4Appearanc...

  • Copper Peptide (GHK)2-CU 49557-75-7

    Copper peptide GHK-CuBasic information of copper peptide GHK-Cu :Product Name(GHK)2-Cu(Copper Peptide)SynonymsGHK-Cu (Copper peptide)CAS #49557-75-7Molecular FormulaC28H46N12O8Cu Molecular Weight742.2...

  • Isoflavones in Soy 574-12-9

    Soybean Extract1.Basic information of Soybean Extract:Product name: Soybean ExtractSource: glycine maxUsed part: germ/bean pulpSpec.: total soy isoflavone 40%, 80% by HPLCNameSoybean Extract PowderTyp...

Basic information of Paclitaxel 33069-62-4

Name

Paclitaxel

Alias

N-BENZYL-BETA-PHENYLISOSERINE ESTER;PACLITAXEL,
TAXUS BREVIFOLIA;PACLITAXEL, TAXUS SPECIES; PACLITAXOL;
PACLITAXEL; TAXOL(TM);taxol a;TAXOL EQUIVALENT

CAS NO.

33069-62-4

Molecular Formula

C47H51NO14

Molecular Weight

853.91

Quality Standard

USP34

Package Size

1g/bag, 25kg/drum or per customer

As dangerous goods

UN1544,Class 6.1,PGIII


Use of Paclitaxel 33069-62-4

  • An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanc ed forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.

COA of Paclitaxel 33069-62-4

Appearance

White or almost white crystalline powder

Identification

FT-IR

HPLC

NMR

Mass

Solubility

Soluble in ethanol, methanol, Chloroform, hardly soluble in water

Specific Optical Rotation

-49.0º ~ -55.0º at 20°C

Melting Point

213°C—216°C

Water

≤1.0%

Residual Solvent

Meets the requirements of ICH

Ethyl Acetate

≤5000ppm

Acetone

≤5000ppm

Methanol

≤3000ppm

Acetic acid

≤5000ppm

Residual of volatile Solvents

Meets the requirements of ICH

Chloroform

≤60ppm

Dichloromethane

≤600ppm

Hexane

≤290ppm

Toluene

≤890ppm

Residue on Ignition

≤0.2%

Bacteria endotoxins

≤0.4 USP EU/mg

Total aerobic microbial count

≤100 cfu/g

Staphylococcus aureus

Absence

Pseudomonas aeruginosa

Absence

Salmonella species

Absence

Escherichia Coli

Absence

Heavy Metals

≤20 ppm


IMPURITIES:

10-Deacetyl Baccatin III

≤0.1%

Baccatin III

≤0.2%

Photodegradant

≤0.1%

10-Deacetyl Paclitaxel

≤0.5%

2-Debenzoylpaclitaxel-2-pentenoate

≤0.7%

Oxetane ring opened, Acetyl and benzoyl

≤0.1%

10-Acetoacetyl paclitaxel

≤0.1%

10-Deacetyl-7-epi-paclitaxel

≤0.3%

7-epi-paclitaxel

≤0.4%

7-epi-paclitaxel

≤0.4%

10,13-Bissidechainpaclitaxel

≤0.5%

7-Acetyl Paclitaxel

≤0.6%



MORE_DETAIL Paclitaxel 33069-62-4

Basic information of Paclitaxel 33069-62-4

Name

Paclitaxel

Alias

N-BENZYL-BETA-PHENYLISOSERINE ESTER;PACLITAXEL,
TAXUS BREVIFOLIA;PACLITAXEL, TAXUS SPECIES; PACLITAXOL;
PACLITAXEL; TAXOL(TM);taxol a;TAXOL EQUIVALENT

CAS NO.

33069-62-4

Molecular Formula

C47H51NO14

Molecular Weight

853.91

Quality Standard

USP34

Package Size

1g/bag, 25kg/drum or per customer

As dangerous goods

UN1544,Class 6.1,PGIII


Use of Paclitaxel 33069-62-4

  • An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanc ed forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.

COA of Paclitaxel 33069-62-4

Appearance

White or almost white crystalline powder

Identification

FT-IR

HPLC

NMR

Mass

Solubility

Soluble in ethanol, methanol, Chloroform, hardly soluble in water

Specific Optical Rotation

-49.0º ~ -55.0º at 20°C

Melting Point

213°C—216°C

Water

≤1.0%

Residual Solvent

Meets the requirements of ICH

Ethyl Acetate

≤5000ppm

Acetone

≤5000ppm

Methanol

≤3000ppm

Acetic acid

≤5000ppm

Residual of volatile Solvents

Meets the requirements of ICH

Chloroform

≤60ppm

Dichloromethane

≤600ppm

Hexane

≤290ppm

Toluene

≤890ppm

Residue on Ignition

≤0.2%

Bacteria endotoxins

≤0.4 USP EU/mg

Total aerobic microbial count

≤100 cfu/g

Staphylococcus aureus

Absence

Pseudomonas aeruginosa

Absence

Salmonella species

Absence

Escherichia Coli

Absence

Heavy Metals

≤20 ppm


IMPURITIES:

10-Deacetyl Baccatin III

≤0.1%

Baccatin III

≤0.2%

Photodegradant

≤0.1%

10-Deacetyl Paclitaxel

≤0.5%

2-Debenzoylpaclitaxel-2-pentenoate

≤0.7%

Oxetane ring opened, Acetyl and benzoyl

≤0.1%

10-Acetoacetyl paclitaxel

≤0.1%

10-Deacetyl-7-epi-paclitaxel

≤0.3%

7-epi-paclitaxel

≤0.4%

7-epi-paclitaxel

≤0.4%

10,13-Bissidechainpaclitaxel

≤0.5%

7-Acetyl Paclitaxel

≤0.6%


Related Articles
Leave a Message Email Us

we will contact you within 24 hours.

  • TEL:+86-0592-5854962
  • FAX:+86-0592-5854960
  • EMAIL: xie@china-sinoway.com
  • ADDRESS:Floor 16, Huicheng Business Center, No. 839, Xiahe Rd., Siming Dist. Xiamen, Fujian, China
//