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Donepezil 120014-06-4 Donepezil 120014-06-4

Donepezil 120014-06-4
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Basic information of Donepezil 120014-06-4

Name

Donepezil

Alias

2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

CAS Number

120014-06-4

Molecular Formula

C24H29NO3

Molecular Weight

379.49

Quality Standard

In house

Package Size

5kg/bag, 10kg/bag, according to your requirement

Brief Introduction

Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in symptomatic treatment drugs.
AD is a kind of memory impairment as the main performance, accompanied by other cognitive
impairment of acquired intelligence decline.


Usage of Donepezil 120014-06-4

  • Donepezil hydrochloride is a second-generation cholinesterase (ChE) inhibitor, its therapeutic effect is reversibly inhibiting acid hydrolysis of acetylcholine acetylcholinesterase (AchE) caused by increased content of acetylcholine receptor sites. Donepezil and there may be other mechanisms, including the disposal of the direct effect of peptides, neurotransmitter receptor or Ca2 + channels. Donepezil for mild to moderate Alzheimer-type dementia.

COA of Donepezil 120014-06-4

ITEMS

SPECIFICATIONS

RESULTS

APPEARANCE

WHITE OR ALMOST WHITE CRYSTALLINE POWDER

CONFORMS

SOLUBILITY

TO MATCH WORKING STANDARD

CONFORMS

IDENTIFICATION

1) BY UV ABSORPTION,TO MATCH WORKING STANDARD

2) BY IR ABSORPTION,TO MATCH WORKING STANDARD



CONFORMS


CONFORMS

MELTING POINT

86-90℃

87.5-88.5℃

RELATED SUBSTANCE

TOTAL

≤1.0%

0.14%

SINGLE IMPURITY (UNKNOWN)

≤0.80%

<0.8%

LOSS ON DRYING

≤1.0%

0.3%

RESIDUE ON IGNITION

≤0.10%

0.02%

HEAVY METAL

≤10 PPM

<10 PPM

ASSAY

≥99.0%

99.87%

CONCLUSION

CONFORMS TO THE ENTERPRISE STANDARD


MORE_DETAIL Donepezil 120014-06-4

Basic information of Donepezil 120014-06-4

Name

Donepezil

Alias

2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one

CAS Number

120014-06-4

Molecular Formula

C24H29NO3

Molecular Weight

379.49

Quality Standard

In house

Package Size

5kg/bag, 10kg/bag, according to your requirement

Brief Introduction

Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in symptomatic treatment drugs.
AD is a kind of memory impairment as the main performance, accompanied by other cognitive
impairment of acquired intelligence decline.


Usage of Donepezil 120014-06-4

  • Donepezil hydrochloride is a second-generation cholinesterase (ChE) inhibitor, its therapeutic effect is reversibly inhibiting acid hydrolysis of acetylcholine acetylcholinesterase (AchE) caused by increased content of acetylcholine receptor sites. Donepezil and there may be other mechanisms, including the disposal of the direct effect of peptides, neurotransmitter receptor or Ca2 + channels. Donepezil for mild to moderate Alzheimer-type dementia.

COA of Donepezil 120014-06-4

ITEMS

SPECIFICATIONS

RESULTS

APPEARANCE

WHITE OR ALMOST WHITE CRYSTALLINE POWDER

CONFORMS

SOLUBILITY

TO MATCH WORKING STANDARD

CONFORMS

IDENTIFICATION

1) BY UV ABSORPTION,TO MATCH WORKING STANDARD

2) BY IR ABSORPTION,TO MATCH WORKING STANDARD



CONFORMS


CONFORMS

MELTING POINT

86-90℃

87.5-88.5℃

RELATED SUBSTANCE

TOTAL

≤1.0%

0.14%

SINGLE IMPURITY (UNKNOWN)

≤0.80%

<0.8%

LOSS ON DRYING

≤1.0%

0.3%

RESIDUE ON IGNITION

≤0.10%

0.02%

HEAVY METAL

≤10 PPM

<10 PPM

ASSAY

≥99.0%

99.87%

CONCLUSION

CONFORMS TO THE ENTERPRISE STANDARD

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