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Dabigatran Intermediates 211914-50-0 Dabigatran Intermediates 211914-50-0

Dabigatran Intermediates 211914-50-0
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Basic Information of Dabigatran Intermediates 211914-50-0

  • CAS No. of key intermediates: 42288-26-6
  • Other Names: 2-(4-Cyanophenylamino)acetic acid
  • MF: C9H8N2O2
  • EINECS No.: 459-560-3
  • Purity: 99%up by HPLC
  • Model Number: Enterprise Standard
  • Appearance: White to off-white powder, White to off-white powder
  • Water by K.F.: NMT 0.5%
  • Any individual impurity: NMT0.1%
  • Total impurity: NMT 0.5%
  • Assay: 98%-102%

Usage of Dabigatran Intermediates 211914-50-0

  • Dabigatran Intermediate,
  • Dabigatran is a novel synthetic direct thrombin inhibitor that is a prodrug of dabigatran, a non-peptide thrombin inhibitor. After oral absorption by the gastrointestinal tract, it is converted in vivo to dabigatran with direct anticoagulant activity. Dabigatran binds to the fibrin-specific binding site of thrombin, preventing the cleavage of fibrinogen to fibrin, thereby blocking the last steps of the coagulation cascade network and thrombus formation. Dabigatran dissociates from fibrin-thrombin binders and exerts reversible anticoagulant effects.

COA of Dabigatran Intermediates 211914-50-0

Dabigatran Intermediates

MORE_DETAIL Dabigatran Intermediates 211914-50-0

Basic Information of Dabigatran Intermediates 211914-50-0

  • CAS No. of key intermediates: 42288-26-6
  • Other Names: 2-(4-Cyanophenylamino)acetic acid
  • MF: C9H8N2O2
  • EINECS No.: 459-560-3
  • Purity: 99%up by HPLC
  • Model Number: Enterprise Standard
  • Appearance: White to off-white powder, White to off-white powder
  • Water by K.F.: NMT 0.5%
  • Any individual impurity: NMT0.1%
  • Total impurity: NMT 0.5%
  • Assay: 98%-102%

Usage of Dabigatran Intermediates 211914-50-0

  • Dabigatran Intermediate,
  • Dabigatran is a novel synthetic direct thrombin inhibitor that is a prodrug of dabigatran, a non-peptide thrombin inhibitor. After oral absorption by the gastrointestinal tract, it is converted in vivo to dabigatran with direct anticoagulant activity. Dabigatran binds to the fibrin-specific binding site of thrombin, preventing the cleavage of fibrinogen to fibrin, thereby blocking the last steps of the coagulation cascade network and thrombus formation. Dabigatran dissociates from fibrin-thrombin binders and exerts reversible anticoagulant effects.

COA of Dabigatran Intermediates 211914-50-0

Dabigatran Intermediates
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